Department of Chemical and Biomolecular Engineering, The Ohio State University, Columbus, Ohio 43210, USA.
J Biomed Mater Res B Appl Biomater. 2010 Feb;92(2):289-97. doi: 10.1002/jbm.b.31514.
A biomaterial system with tunable mechanical properties was synthesized through random copolymerization of hexyl methacrylate, methyl methacrylate, and methacrylic acid. The composition, molecular weight, water absorption, glass transition temperature, and tensile properties of the polymer system were characterized, and the biocompatibility of the material was demonstrated by the ability of human umbilical vein endothelial cells to adhere, proliferate, and spread on the polymer surface. No difference was observed in the behavior of the endothelial cells on the materials regardless of material stiffness.
通过随机共聚甲基丙烯酸己酯、甲基丙烯酸甲酯和甲基丙烯酸合成了一种力学性能可调的生物材料体系。对聚合物体系的组成、分子量、吸水率、玻璃化转变温度和拉伸性能进行了表征，并通过人脐静脉内皮细胞在聚合物表面黏附、增殖和铺展的能力证明了材料的生物相容性。无论材料的硬度如何，内皮细胞在材料上的行为均无差异。
