Brodzka Renata, Trzcinka-Ochocka Małgorzata
Instytut Medycyny Pracy im. prof. J. Nofera, Zakład Zagrozeń Chemicznych, Lódź.
Med Pr. 2009;60(4):303-14.
Mercury concentration in human hair is used as an indicator of long-term environmental exposure to mercury. Over 90% of mercury in hair occur in the metylmercury form. Exposure to mercury almost entirely results from the consumption of seafood and meat of big sea mammals. This paper presents a review of toxic effects of mercury, biological monitoring of exposure to mercury and biological levels of mercury in hair and blood of people consuming a variety of fish diets. It also describes the methods most often used for preliminary sample preparation and applied to determining mercury hair levels. Validation parameters of the method for the determination of mercury in hair, developed and applied by the Nofer Institute of Occupational Medicine, is also presented.
人体头发中的汞含量被用作长期环境汞暴露的指标。头发中超过90%的汞以甲基汞的形式存在。汞暴露几乎完全源于食用海鲜和大型海洋哺乳动物的肉类。本文综述了汞的毒性作用、汞暴露的生物监测以及食用各种鱼类饮食人群头发和血液中的汞生物水平。还描述了最常用于初步样品制备并用于测定头发汞含量的方法。同时还介绍了由诺费职业医学研究所开发并应用的头发汞测定方法的验证参数。
