Levy-Bercowski Daniel, Abreu Amara, DeLeon Eladio, Looney Stephen, Stockstill John, Weiler Michael, Santiago Pedro E
Orthodontic Department and Medical College of Georgia Craniofacial Center, Augusta, 30912-1230, USA.
Cleft Palate Craniofac J. 2009 Sep;46(5):521-8. doi: 10.1597/07-236.1. Epub 2008 Dec 24.
To outline three main categories of nasoalveolar molding complications, describe their etiologies and manifestations, and prescribe preventive and palliative therapy for their proper management. Estimates of the incidence of each complication also are provided.
Data were collected retrospectively from the charts of 27 patients with complete unilateral cleft lip and palate treated by the first author (D.L.-B.) at the University of Puerto Rico (n = 12) and the Medical College of Georgia (n = 15). Confidence intervals for the true incidence of each complication were calculated using exact methods based on the binomial distribution. A significance level of .05 was used for all statistical tests.
Of the soft and hard tissue complications considered, only one (tissue irritation) had an estimated incidence greater than 10%. Compliance issues were of greater concern, with an estimated incidence of 30% for broken appointments and an estimated incidence of 26% for removal of the nasoalveolar molding appliance by the tongue.
Although benefits outnumber the complications, it is important to address all complications in order to prevent any deleterious outcomes.
概述鼻牙槽塑形并发症的三大主要类别，描述其病因及表现，并给出预防和姑息治疗方法以妥善处理这些并发症。同时还提供了每种并发症发生率的估计值。
回顾性收集了27例单侧完全性唇腭裂患者的病历资料，这些患者分别由第一作者（D.L.-B.）在波多黎各大学（12例）和佐治亚医学院（15例）进行治疗。基于二项分布，采用精确方法计算每种并发症实际发生率的置信区间。所有统计检验的显著性水平均设定为0.05。
在考虑的软硬组织并发症中，只有一种（组织刺激）的估计发生率超过10%。依从性问题更值得关注，预约中断的估计发生率为30%，用舌头移除鼻牙槽塑形矫治器的估计发生率为26%。
尽管益处多于并发症，但为防止出现任何有害后果，对所有并发症进行处理很重要。
