Mubarak Muhammed, Kazi Javed Iqbal
Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan.
Ultrastruct Pathol. 2009 Dec;33(6):260-4. doi: 10.3109/01913120903296952.
To determine the role of immunofluorescence (IF) and electron microscopy (EM) in the evaluation of renal biopsies in a developing country, the authors carried out a study in 200 patients with nephrotic syndrome. Renal biopsies were studied by light microscopy, IF, and EM. IF study was useful in all, being essential in 23.5% and helpful in remaining cases. EM was useful in 94.5% cases, being essential in 43% and helpful in 51.5% cases. The results demonstrate that IF and EM are essential in the evaluation of renal biopsies in nephrotic syndrome and these should be employed in the pathologic evaluation of renal biopsies.
为确定免疫荧光（IF）和电子显微镜检查（EM）在一个发展中国家肾活检评估中的作用，作者对200例肾病综合征患者进行了一项研究。肾活检通过光学显微镜、IF和EM进行研究。IF研究在所有病例中均有用，在23.5%的病例中是必不可少的，在其余病例中也有帮助。EM在94.5%的病例中有用，在43%的病例中是必不可少的，在51.5%的病例中也有帮助。结果表明，IF和EM在肾病综合征肾活检评估中是必不可少的，应将它们用于肾活检的病理评估。
