Suppr超能文献

资源匮乏地区的儿科肾脏病学

Paediatric nephrology in under-resourced areas.

作者信息

Banerjee Sushmita, Kamath Nivedita, Antwi Sampson, Bonilla-Felix Melvin

机构信息

Calcutta Medical Research Institute, Kolkata, India.

St John's Medical College Hospital, Bangalore, India.

出版信息

Pediatr Nephrol. 2022 May;37(5):959-972. doi: 10.1007/s00467-021-05059-y. Epub 2021 Apr 10.

Abstract

BACKGROUND

Nearly 50% of the world population and 60% of children aged 0 to 14 years live in low- or lower-middle-income countries. Paediatric nephrology (PN) in these countries is not a priority for allocation of limited health resources. This article explores advancements made and persisting limitations in providing optimal PN services to children in such under-resourced areas (URA).

METHODS

Medline, PubMed and Google Scholar online databases were searched for articles pertaining to PN disease epidemiology, outcome, availability of services and infrastructure in URA. The ISN and IPNA offices were contacted for data, and two online questionnaire surveys of IPNA membership performed. Regional IPNA members were contacted for further detailed information.

RESULTS

There is a scarcity of published data from URA; where available, prevalence of PN diseases, managements and outcomes are often reported to be different from high income regions. Deficiencies in human resources, fluoroscopy, nuclear imaging, immunofluorescence, electron microscopy and genetic studies were identified. Several drugs and maintenance kidney replacement therapy are inaccessible to the majority of patients. Despite these issues, regional efforts with support from international bodies have led to significant advances in PN services and infrastructure in many URA.

CONCLUSIONS

Equitable distribution and affordability of PN services remain major challenges in URA. The drive towards acquisition of regional data, advocacy to local government and non-government agencies and partnership with international support bodies needs to be continued. The aim is to optimise and achieve global parity in PN training, investigations and treatments, initially focusing on preventable and reversible conditions.

摘要

背景

世界近50%的人口以及60%的0至14岁儿童生活在低收入或中低收入国家。在这些国家,儿科肾脏病学(PN)并非有限卫生资源分配的优先事项。本文探讨了在资源匮乏地区(URA)为儿童提供最佳PN服务方面取得的进展和持续存在的限制。

方法

检索Medline、PubMed和谷歌学术在线数据库,查找与URA的PN疾病流行病学、结局、服务可及性和基础设施相关的文章。联系国际肾脏病学会(ISN)和国际儿科肾脏病协会(IPNA)办公室获取数据,并对IPNA成员进行了两项在线问卷调查。联系IPNA区域成员获取进一步详细信息。

结果

URA发表的数据稀缺;在有数据的情况下,PN疾病的患病率、管理和结局通常报告与高收入地区不同。已确定人力资源、荧光镜检查、核成像、免疫荧光、电子显微镜和基因研究方面存在不足。大多数患者无法获得几种药物和维持性肾脏替代治疗。尽管存在这些问题,但在国际机构的支持下,区域努力已在许多URA的PN服务和基础设施方面取得了重大进展。

结论

PN服务的公平分配和可负担性在URA仍然是主要挑战。获取区域数据、向地方政府和非政府机构进行宣传以及与国际支持机构建立伙伴关系的努力需要继续。目标是在PN培训、检查和治疗方面实现优化并达到全球均等,最初重点关注可预防和可逆的病症。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验