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丹麦ADDITION研究中筛查发现的2型糖尿病患者对指南的依从性

Adherence to guidelines in people with screen-detected type 2 diabetes, ADDITION, Denmark.

作者信息

Juul Lise, Sandbaek Annelli, Foldspang Anders, Frydenberg Morten, Borch-Johnsen Knut, Lauritzen Torsten

机构信息

Department of General Practice, School of Public Health, Aarhus University, Gentofte, Denmark.

出版信息

Scand J Prim Health Care. 2009;27(4):223-31. doi: 10.3109/02813430903279117.

Abstract

OBJECTIVE

In people with screen-detected type 2 diabetes in primary care, (1) to assess adherence to guidelines, recommending consultation with the GP every three months and treatment initiation with an ACE inhibitor or an angiotensin-II receptor antagonist when systolic BP was > 120 mmHg and/or diastolic BP was > 80 mmHg, and (2) to identify predictors for adherence.

DESIGN

Prospective follow-up of a fixed cohort of patients.

SETTING

Fifty-four Danish general practices.

SUBJECTS AND MAIN OUTCOME MEASURES

A total of 361 people with screen-detected type 2 diabetes were followed up for 410 days to assess planned consultations with their GP and recording of BP. Some 226 people, with BP recorded above guideline threshold(s) and where treatment was not already initiated, were followed for up to 410 days to monitor prescription redemption.

RESULTS

At 3, 6, 9 and 12 months 80%, 77%, 74%, and 73% of the cohort attended a consultation. A total of 89% of the cohort attended two of the four planned consultations. The probability of redeemed prescriptions for an ACE inhibitor or an angiotensin-II receptor antagonist according to the guideline during the first year following diagnosis was 51%. High initial BP was associated with prescription redemption. No other analysed individual or organisational characteristics were found to be associated with treatment initiation.

CONCLUSION

The consultation attendance was reasonably high, and treatment initiation with an ACE inhibitor or an angiotensin-II receptor antagonist according to the guideline was found in half of the cases. High initial BP increased the probability of treatment initiation.

摘要

目的

在初级保健中经筛查发现患有2型糖尿病的人群中,(1)评估对指南的依从性,该指南建议每三个月与全科医生进行一次会诊,当收缩压>120 mmHg和/或舒张压>80 mmHg时开始使用血管紧张素转换酶(ACE)抑制剂或血管紧张素II受体拮抗剂进行治疗;(2)确定依从性的预测因素。

设计

对一组固定患者进行前瞻性随访。

地点

54家丹麦普通诊所。

研究对象和主要观察指标

共有361名经筛查发现患有2型糖尿病的患者接受了410天的随访,以评估与他们的全科医生进行的计划会诊以及血压记录情况。约226名血压记录高于指南阈值且尚未开始治疗的患者接受了长达410天的随访,以监测处方药物的领取情况。

结果

在3、6、9和12个月时,该队列中80%、77%、74%和73%的患者进行了会诊。该队列中共有89%的患者参加了四次计划会诊中的两次。在诊断后的第一年,根据指南领取ACE抑制剂或血管紧张素II受体拮抗剂处方药物治疗的概率为51%。初始血压高与处方药物领取有关。未发现其他分析的个体或组织特征与治疗开始有关。

结论

会诊出席率相当高,并且在一半的病例中发现了根据指南使用ACE抑制剂或血管紧张素II受体拮抗剂开始治疗的情况。初始血压高增加了开始治疗的概率。

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Screening for type 2 diabetes mellitus.2型糖尿病筛查
Cochrane Database Syst Rev. 2020 May 29;5(5):CD005266. doi: 10.1002/14651858.CD005266.pub2.

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