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眼睑复发性非典型纤维黄色瘤的石蜡组织学切片及延迟修复

Paraffin histology sections and delayed repair in recurrent atypical fibroxanthoma of the eyelid.

作者信息

Paramanathan Nirosha, Gal Andrew, Benger Ross

机构信息

Drummoyne Eye Surgical Centre, Sydney, Australia.

出版信息

Orbit. 2009;28(6):380-2. doi: 10.3109/01676830903071216.

DOI:10.3109/01676830903071216
PMID:19929664
Abstract

We present a report of a recurrent atypical fibroxanthoma (AFX), a tumour known rarely to involve the eyelid. A 61 year-old male was referred after reappearance of a lower eyelid AFX within two months of resection. The neoplastic spindle cells at the periphery of an AFX may be difficult to differentiate from dermal fibroblasts in frozen sections. Paraffin sections provide better histological definition and thus greater accuracy in determining completeness of excision. The patient's recurrent tumour was surgically excised and overnight paraffin sections were used to obtain margin clearance, before secondary reconstruction. The tumour required re-excision on three occasions before clearance was achieved. The patient remains tumour free at 12 months' follow-up.

摘要

我们报告一例复发性非典型纤维黄色瘤(AFX),这是一种罕见累及眼睑的肿瘤。一名61岁男性在切除下睑AFX后两个月内肿瘤复发,前来就诊。在冰冻切片中,AFX周边的肿瘤性梭形细胞可能难以与真皮成纤维细胞区分。石蜡切片能提供更好的组织学清晰度,从而在确定切除完整性方面具有更高的准确性。患者的复发性肿瘤通过手术切除,并在二次重建前使用过夜石蜡切片来获得切缘阴性。该肿瘤在达到切缘阴性之前需要三次重新切除。患者在12个月的随访中无肿瘤复发。

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引用本文的文献

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Atypical Fibroxanthoma of the Bulbar Conjunctiva: A Unique Case Describing the Pathology, Clinical Presentation, and Management.球结膜非典型纤维黄色瘤:描述病理、临床表现及治疗的独特病例
Ocul Oncol Pathol. 2018 Apr;4(3):152-156. doi: 10.1159/000480088. Epub 2017 Oct 20.
2
Recurrent atypical fibroxanthoma of the limbus.复发性角膜缘非典型纤维黄色瘤
BMJ Case Rep. 2013 Mar 15;2013:bcr2013008762. doi: 10.1136/bcr-2013-008762.