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心脏手术患者的左心室舒张功能障碍;心脏外科医生和心脏麻醉医生的观点

Left ventricular diastolic dysfunction of the cardiac surgery patient; a point of view for the cardiac surgeon and cardio-anesthesiologist.

作者信息

Apostolakis Efstratios E, Baikoussis Nikolaos G, Parissis Haralabos, Siminelakis Stavros N, Papadopoulos Georgios S

机构信息

Cardiothoracic Surgery Department, University of Patras, School of Medicine, Patras, Greece.

出版信息

J Cardiothorac Surg. 2009 Nov 24;4:67. doi: 10.1186/1749-8090-4-67.

Abstract

BACKGROUND

Left ventricular diastolic dysfunction (DD) is defined as the inability of the ventricle to fill to a normal end-diastolic volume, both during exercise as well as at rest, while left atrial pressure does not exceed 12 mm Hg. We examined the concept of left ventricular diastolic dysfunction in a cardiac surgery setting.

MATERIALS AND METHODS

Literature review was carried out in order to identify the overall experience of an important and highly underestimated issue: the unexpected adverse outcome due to ventricular stiffness, following cardiac surgery.

RESULTS

Although diverse group of patients for cardiac surgery could potentially affected from diastolic dysfunction, there are only few studies looking in to the impact of DD on the postoperative outcome; Trans-thoracic echo-cardiography (TTE) is the main stay for the diagnosis of DD. Intraoperative trans-oesophageal (TOE) adds to the management. Subgroups of DD can be defined with prognostic significance.

CONCLUSION

DD with elevated left ventricular end-diastolic pressure can predispose to increased perioperative mortality and morbidity. Furthermore, DD is often associated with systolic dysfunction, left ventricular hypertrophy or indeed pulmonary hypertension. When the diagnosis of DD is made, peri-operative attention to this group of patients becomes mandatory.

摘要

背景

左心室舒张功能障碍(DD)被定义为在运动和静息状态下,心室无法充盈至正常的舒张末期容积,同时左心房压力不超过12毫米汞柱。我们在心脏手术背景下研究了左心室舒张功能障碍的概念。

材料与方法

进行文献综述,以确定一个重要且被严重低估的问题的总体情况:心脏手术后因心室僵硬度导致的意外不良后果。

结果

尽管不同的心脏手术患者群体都可能受到舒张功能障碍的影响,但仅有少数研究探讨了舒张功能障碍对术后结局的影响;经胸超声心动图(TTE)是诊断舒张功能障碍的主要手段。术中经食管超声心动图(TOE)有助于管理。舒张功能障碍的亚组具有预后意义。

结论

左心室舒张末期压力升高的舒张功能障碍可能导致围手术期死亡率和发病率增加。此外,舒张功能障碍常与收缩功能障碍、左心室肥厚或肺动脉高压相关。一旦诊断出舒张功能障碍,对这组患者进行围手术期关注就变得至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d46/2788544/bc8ca99dd811/1749-8090-4-67-1.jpg

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