Structural flexibility of Aib-containing peptides: the N-terminal tripeptide of trichotoxin.
作者信息
Gessmann R, Brueckner H, Kokkinidis M
机构信息
Dept. of Biology, University of Crete, Greece.
出版信息
Biochem Biophys Res Commun. 1991 Jan 31;174(2):878-84. doi: 10.1016/0006-291x(91)91499-3.
PMID:1993078
Abstract
The sequence Aib-Gly-Aib which corresponds to the N-terminus of the microheterogeneous peptide antibiotic trichotoxin has been studied crystallographically in the context of different protecting groups. Peptides Ac-Aib-Gly-Aib-OH (A) and Z-Aib-Gly-Aib-OH (B) form beta-turns. Both peptides show a remarkable conformational flexibility forming a large variety of beta-turns of different types.
摘要
Zotero 插件