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科萨科夫患者的虚构与实验诱导的虚假记忆。

Confabulation versus experimentally induced false memories in Korsakoff patients.

机构信息

Department of Psychology, University of Leuven, Belgium.

出版信息

J Neuropsychol. 2010 Sep;4(Pt 2):211-30. doi: 10.1348/174866409X478231. Epub 2009 Nov 21.

Abstract

The present study focuses on both the clinical symptom of confabulation and experimentally induced false memories in patients suffering from Korsakoff's syndrome. Despite the vast amount of case studies of confabulating patients and studies investigating false memories in the Deese-Roediger-McDermott (DRM) paradigm, the nature of Korsakoff patients' confabulatory behaviour and its association with DRM false memories have been rarely examined. Hence, the first aim of the present study was to evaluate confabulatory responses in a large sample of chronic Korsakoff patients and matched controls by means of the Dalla Barba Confabulation Battery. Second, the association between (provoked) confabulation and the patients' DRM false recognition performance was investigated. Korsakoff patients mainly confabulated in response to questions about episodic memory and questions to which the answer was unknown. A positive association was obtained between confabulation and the tendency to accept unstudied distractor words as being old in the DRM paradigm. On the other hand, there was a negative association between confabulation and false recognition of critical lures. The latter could be attributed to the importance of strategic retrieval at delayed memory testing.

摘要

本研究同时关注柯萨科夫综合征患者的临床虚构症状和实验诱导的虚假记忆。尽管有大量关于虚构患者的病例研究和在 Deese-Roediger-McDermott (DRM) 范式中研究虚假记忆的研究,但柯萨科夫患者虚构行为的性质及其与 DRM 虚假记忆的关联很少被研究。因此,本研究的第一个目的是通过 Dalla Barba 虚构症测试工具包评估大量慢性柯萨科夫患者和匹配对照组的虚构反应。其次,研究了(诱发的)虚构与患者 DRM 虚假识别表现之间的关联。柯萨科夫患者主要在回答关于情节记忆的问题和答案未知的问题时虚构。在 DRM 范式中,虚构与接受未学习的分心词为旧的倾向呈正相关。另一方面,虚构与关键诱饵的错误识别呈负相关。这可以归因于在延迟记忆测试中策略性检索的重要性。

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