School of Psychology, Cardiff University, Cardiff, UK.
Psychiatry Res. 2010 Jul 30;178(2):260-5. doi: 10.1016/j.psychres.2009.02.006. Epub 2010 May 14.
Delusions are fixed 'false beliefs' and, although a hallmark feature of schizophrenia, no previous study has examined if delusions might be related to 'false memories'. We used the classic Deese-Roediger-McDermott (DRM) paradigm to compare false memory production in schizophrenia patients who were currently experiencing delusions (ED), patients not experiencing delusions (ND) and healthy control participants. The ED group recalled twice as many false-positive memories (i.e., memory for words not previously seen) as both the controls and crucially, the ND group. Both patient groups also recognised fewer correct words than the healthy controls and both showed greater confidence in their false memories; however, on the recognition task, the ED group made more false-negative (i.e. rejecting previously seen words) high confidence responses than the ND group.
妄想是固定的“虚假信念”,尽管是精神分裂症的一个显著特征,但以前没有研究检查妄想是否与“虚假记忆”有关。我们使用经典的 Deese-Roediger-McDermott (DRM) 范式,比较了当前经历妄想的精神分裂症患者 (ED 组)、未经历妄想的患者 (ND 组) 和健康对照组在虚假记忆产生方面的差异。ED 组回忆的虚假阳性记忆(即对以前未见过的单词的记忆)是对照组和关键的 ND 组的两倍。两组患者的正确单词识别率都低于健康对照组,并且都表现出对虚假记忆的更高置信度;然而,在识别任务中,ED 组比 ND 组做出更多的虚假阴性(即拒绝以前见过的单词)高置信度反应。