Cannon Coralie Zegre, Godfrey Virginia L, King-Herbert Angela, Nielsen Judith N
University of North Carolina Department of Pathology and Laboratory Medicine, Chapel Hill, North Carolina, USA.
J Am Assoc Lab Anim Sci. 2009 Nov;48(6):795-800.
An 8-y-old gilt was evaluated after the onset of hemorrhagic perineal discharge. Uterine adenocarcinoma with metastases to the lungs and regional lymph nodes was diagnosed at necropsy. Tumor cells lacked expression of estrogen receptor alpha and progesterone receptor. This case represents the first reported uterine adenocarcinoma in a research pig and the first swine uterine neoplasia in which steroid hormone receptor expression was evaluated.
一头8岁的小母猪在出现会阴出血性分泌物后接受了评估。尸检诊断为子宫腺癌伴肺和局部淋巴结转移。肿瘤细胞缺乏雌激素受体α和孕激素受体的表达。该病例是研究用猪中首次报道的子宫腺癌,也是首次评估类固醇激素受体表达的猪子宫肿瘤。