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Expression of estrogen receptor-related receptor isoforms and clinical significance in endometrial adenocarcinoma.雌激素受体相关受体亚型在子宫内膜腺癌中的表达及其临床意义
Int J Gynecol Cancer. 2006 Mar-Apr;16(2):827-33. doi: 10.1111/j.1525-1438.2006.00527.x.
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Diffuse cystic endometrial hyperplasia and metastatic endometrial adenocarcinoma in a vietnamese pot-bellied pig (Sus scrofa).一只越南大肚猪(Sus scrofa)的弥漫性囊性子宫内膜增生和转移性子宫内膜腺癌
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Uterine smooth muscle tumors in potbellied pigs (Sus scrofa) resemble human fibroids: a potential animal model.大肚猪(猪属)的子宫平滑肌瘤与人类子宫肌瘤相似:一种潜在的动物模型。
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Well-differentiated endometrial adenocarcinomas and poorly differentiated mixed mullerian tumors have altered ER and PR isoform expression.高分化子宫内膜腺癌和低分化混合性苗勒管肿瘤的雌激素受体(ER)和孕激素受体(PR)亚型表达发生改变。
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一头8岁小母猪的转移性子宫腺癌

Metastatic uterine adenocarcinoma in an 8-year-old gilt.

作者信息

Cannon Coralie Zegre, Godfrey Virginia L, King-Herbert Angela, Nielsen Judith N

机构信息

University of North Carolina Department of Pathology and Laboratory Medicine, Chapel Hill, North Carolina, USA.

出版信息

J Am Assoc Lab Anim Sci. 2009 Nov;48(6):795-800.

PMID:19930830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2786936/
Abstract

An 8-y-old gilt was evaluated after the onset of hemorrhagic perineal discharge. Uterine adenocarcinoma with metastases to the lungs and regional lymph nodes was diagnosed at necropsy. Tumor cells lacked expression of estrogen receptor alpha and progesterone receptor. This case represents the first reported uterine adenocarcinoma in a research pig and the first swine uterine neoplasia in which steroid hormone receptor expression was evaluated.

摘要

一头8岁的小母猪在出现会阴出血性分泌物后接受了评估。尸检诊断为子宫腺癌伴肺和局部淋巴结转移。肿瘤细胞缺乏雌激素受体α和孕激素受体的表达。该病例是研究用猪中首次报道的子宫腺癌,也是首次评估类固醇激素受体表达的猪子宫肿瘤。