Janssen C W, Maartmann-Moe H, Lie R T, Matre R
Department of Surgery, University of Bergen, Norway.
APMIS. 1991 Jan;99(1):78-82. doi: 10.1111/j.1699-0463.1991.tb05122.x.
A twelve-year series of 375 patients with gastric carcinoma has been studied. Primary tumours were classified as intestinal type (58%) or diffuse (26%), whereas 16% were unclassifiable. The relative age and sex incidence rates of intestinal type and diffuse gastric carcinoma were estimated using the age and sex distribution of individuals in Norway as the basis for calculation. There was no difference in the rates of diffuse gastric carcinoma between the sexes. On the other hand, the rate of men with intestinal type carcinoma was more than twice as high as that of women. This difference was consistent within each age group from adolescence to senescence. The findings indicate that Laurén's two types of gastric carcinoma are aetiologically different. The rates of both types increased with age up to the 70-79 age group, whereas the rates in octogenarians tended to be lower than in septuagenarians. A comparison of our data with the data of incidence of gastric cancer in Norway indicates that some of the older patients do not come for surgery.
对375例胃癌患者进行了为期12年的研究。原发性肿瘤分为肠型(58%)或弥漫型(26%),而16%无法分类。以挪威人群的年龄和性别分布为计算基础,估算了肠型和弥漫型胃癌的相对年龄和性别发病率。弥漫型胃癌的发病率在性别上无差异。另一方面,肠型癌男性的发病率是女性的两倍多。从青春期到老年,每个年龄组内这种差异都是一致的。研究结果表明,劳伦分类的两种类型的胃癌在病因上是不同的。两种类型的发病率均随年龄增长而上升,直至70 - 79岁年龄组,而八旬老人的发病率往往低于七旬老人。将我们的数据与挪威胃癌发病率数据进行比较表明,一些老年患者未接受手术治疗。