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氧化铜丝颗粒对绵羊和山羊胃肠道线虫的疗效。

Efficacy of copper oxide wire particles against gastrointestinal nematodes in sheep and goats.

机构信息

Fort Valley State University, Fort Valley, GA 31030, USA.

出版信息

Vet Parasitol. 2010 Feb 26;168(1-2):93-6. doi: 10.1016/j.vetpar.2009.10.004. Epub 2009 Oct 29.

Abstract

Profitable sheep and goat production in the USA is severely limited by gastrointestinal nematode (GIN) parasitism, particularly by Haemonchus contortus. Copper oxide wire particles (COWP) have anti-parasitic properties in the diet of small ruminants, but efficacy of COWP may differ between sheep and goats. In a study with weaned kids (Kiko x Spanish cross, 6 months old) and lambs (Katahdin or Dorper x Blackface crosses, 5 months old), grazing the same pasture area in Central Georgia, 2g of COWP in a gel capsule was given to half the animals of each species, while the other half were given no COWP. Fecal and blood samples were taken weekly to determine GIN fecal egg counts (FEC) and blood packed cell volume (PCV). After COWP treatment, animals were grazed for 4 weeks and then slaughtered, with adult GIN recovered from the abomasum and small intestines for counting and identification to species. For both sheep and goats, COWP treatment reduced EPG (P<0.05), increased PCV (P<0.05), and lowered abomasal GIN numbers (P<0.05). For EPG, these differences were 82.5 and 90.5% for sheep and goats, respectively, 26 days after treatment, while adult H. contortus were 67.2 and 85.8% lower for COWP-treated sheep and goats, respectively. In this study, COWP treatment was equally effective against H. contortus infection in lambs and kids and appears to be an effective method of controlling H. contortus infection for up to 6 weeks in small ruminants following weaning.

摘要

美国的绵羊和山羊生产受到胃肠道线虫(GIN)寄生虫的严重限制,尤其是捻转血矛线虫(Haemonchus contortus)。氧化铜线颗粒(COWP)在小反刍动物的饮食中具有抗寄生虫特性,但 COWP 的功效在绵羊和山羊之间可能有所不同。在一项针对断奶幼崽(Kiko x 西班牙杂交,6 个月大)和羔羊(Katahdin 或 Dorper x 黑脸杂交,5 个月大)的研究中,这些动物在佐治亚州中部的同一牧场放牧,每只动物的一半喂食 2g COWP 胶囊,另一半则不喂食 COWP。每周采集粪便和血液样本以确定 GIN 粪便卵计数(FEC)和血液红细胞压积(PCV)。在 COWP 治疗后,动物放牧 4 周,然后屠宰,从皱胃和小肠中回收成年 GIN 进行计数和鉴定。对于绵羊和山羊,COWP 处理均降低了 EPG(P<0.05),增加了 PCV(P<0.05),并降低了皱胃 GIN 数量(P<0.05)。EPG 方面,治疗后 26 天,绵羊和山羊的差异分别为 82.5%和 90.5%,COWP 处理的绵羊和山羊的成年捻转血矛线虫分别降低了 67.2%和 85.8%。在这项研究中,COWP 处理对羔羊和幼崽的捻转血矛线虫感染同样有效,并且在断奶后 6 周内似乎是一种有效控制小反刍动物捻转血矛线虫感染的方法。

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