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越南海防地区儿童轮状病毒腹泻的分子流行病学研究:G3 轮状病毒的出现。

Molecular epidemiology of rotavirus diarrhoea among children in Haiphong, Vietnam: the emergence of G3 rotavirus.

机构信息

National Institute of Hygiene and Epidemiology, Vietnam.

出版信息

Vaccine. 2009 Nov 20;27 Suppl 5:F75-80. doi: 10.1016/j.vaccine.2009.08.074.

Abstract

From September 2006- October 2007 hospital-based surveillance was conducted in Haiphong, Vietnam among children less than age 5 years hospitalized for diarrhoea to determine the distribution of G and P types and electropherotypes of rotavirus. Of note, the emergence of G3P[8] was identified and the strain was predominant among rotaviruses detected. More than 90% of G3P[8] electropherotyped strains shared an identical electropherotype, indicating they were of a single origin and their VP7 sequences were similar to those reported from Japan and China. This abrupt emergence of a novel G3 strains underscores the continued need for quality rotavirus surveillance.

摘要

从 2006 年 9 月到 2007 年 10 月,越南海防的一家医院对住院的 5 岁以下腹泻儿童进行了基于医院的监测,以确定轮状病毒 G 和 P 型以及电泳型的分布。值得注意的是,鉴定出 G3P[8]的出现,并且该毒株是检测到的轮状病毒中的主要毒株。超过 90%的 G3P[8]电泳型毒株具有相同的电泳型,表明它们来自单一来源,其 VP7 序列与来自日本和中国的报道相似。这种新型 G3 株的突然出现突出表明,仍需要进行高质量的轮状病毒监测。

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