Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan.
AJR Am J Roentgenol. 2009 Dec;193(6):1607-14. doi: 10.2214/AJR.09.2675.
The purpose of this study was to assess the value of the fast STIR sequence in comparison with the T1-weighted fat-suppressed contrast-enhanced sequence in the evaluation of soft-tissue tumors.
Sixty-seven soft-tissue tumors imaged with both STIR and T1-weighted fat-suppressed contrast-enhanced sequences were evaluated. The signal-to-noise and contrast-to-noise ratios of the tumors in comparison with normal muscle, bone marrow, and fat were measured. Subjective image contrast between soft-tissue tumors and the nearest normal tissue was evaluated by two observers. The observers classified the soft-tissue tumors as benign or malignant using a 5-point scale, and sensitivity, specificity, and accuracy were calculated. The results of the two readings were assessed with receiver operating characteristic analysis.
The contrast-to-noise ratios of all tumors in comparison with muscle (p < 0.01), bone marrow (p < 0.05), and fat (p < 0.05) were significantly higher on the fast STIR images than on the T1-weighted fat-suppressed contrast-enhanced images. Both observers' mean ratings of benign, malignant, and all tumors in comparison with muscle on fast STIR images were significantly higher than those on T1-weighted fat-suppressed contrast-enhanced images. For both observers, the mean sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve in evaluation of the fast STIR images did not differ significantly from those in evaluation of the T1-weighted fat-suppressed contrast-enhanced images.
The fast STIR sequence is excellent for evaluation of soft-tissue tumors, and contrast-enhancement is not always needed.
本研究旨在评估快速 STIR 序列在软组织肿瘤评估中的价值，并与 T1 加权脂肪抑制对比增强序列进行比较。
对 67 例同时行 STIR 和 T1 加权脂肪抑制对比增强序列检查的软组织肿瘤患者进行评估。测量肿瘤与正常肌肉、骨髓和脂肪的信噪比和对比噪声比。两名观察者评估软组织肿瘤与最近的正常组织之间的主观图像对比度。观察者使用 5 分制对软组织肿瘤进行良性或恶性分类，并计算敏感性、特异性和准确性。对两种阅读结果进行受试者工作特征分析。
与 T1 加权脂肪抑制对比增强图像相比，所有肿瘤在快速 STIR 图像上与肌肉（p < 0.01）、骨髓（p < 0.05）和脂肪（p < 0.05）的对比噪声比均显著升高。两位观察者对快速 STIR 图像上的良性、恶性和所有肿瘤与肌肉的平均评分均显著高于 T1 加权脂肪抑制对比增强图像。对于两位观察者，快速 STIR 图像评估的平均敏感性、特异性、准确性和受试者工作特征曲线下面积与 T1 加权脂肪抑制对比增强图像评估的结果均无显著差异。
快速 STIR 序列是评估软组织肿瘤的极佳方法，并不总是需要增强。
