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仅后路全脊椎整块切除术治疗恶性原发性脊柱肿瘤:解剖学考虑和手术要点。

Posterior-only approach for total en bloc spondylectomy for malignant primary spinal neoplasms: anatomic considerations and operative nuances.

机构信息

Department of Neurological Surgery, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA.

出版信息

Neurosurgery. 2009 Dec;65(6 Suppl):173-81; discussion 181. doi: 10.1227/01.NEU.0000345630.47344.17.

Abstract

MALIGNANT PRIMARY SPINAL tumors are rare tumors that are locally invasive and can metastasize. The majority of these tumors have a poor response rate to chemotherapy and conventional radiotherapy. Studies have shown that long-term survival and the potential for cure is best achieved with en bloc surgical excision of these tumors with negative surgical margins. Total en bloc spondylectomy involves removal of vertebral segment(s) in whole to achieve wide tumor excision. Total en bloc spondylectomy can be performed through staged or combined anterior and posterior approaches, or from a posterior-only approach. The posterior-only approach offers the advantage of achieving complete tumor excision and circumferential spinal reconstruction in a single setting. In this report, we discuss the operative management of malignant primary vertebral tumors using the posterior-only approach for total en bloc spondylectomy. The oncological considerations and surgical nuances that allow for safe but aggressive surgical excision of primary spinal tumors to achieve favorable oncological and neurological outcomes are highlighted.

摘要

恶性原发性脊柱肿瘤是局部侵袭性和转移性的罕见肿瘤。这些肿瘤大多数对化疗和常规放疗的反应率较差。研究表明,通过整块切除肿瘤并获得阴性切缘,可获得长期生存和治愈的潜力。整块脊柱切除术包括整块切除脊柱节段,以实现广泛的肿瘤切除。整块脊柱切除术可通过分期或前后联合入路,或单一后路入路进行。后路入路的优点是可在单个部位实现完全肿瘤切除和脊柱环周重建。在本报告中,我们讨论了使用后路整块脊柱切除术治疗恶性原发性脊柱肿瘤的手术治疗方法。强调了肿瘤学考虑因素和手术细节,这些因素允许安全而激进地切除原发性脊柱肿瘤,以实现良好的肿瘤学和神经学结果。

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