James M E, Rubin C P, Willis S E
Department of Psychiatry and Gynecology, Emory University School of Medicine, Grady Memorial Hospital, Atlanta, Georgia 30335.
Gen Hosp Psychiatry. 1991 Jan;13(1):4-8. doi: 10.1016/0163-8343(91)90003-f.
In a sample of 55 human immunodeficiency virus (HIV)-seropositive pregnant patients, a history of drug abuse was significantly associated with increased psychopathology, particularly depression and personality disorders. Psychiatric disorders preceded the HIV diagnosis in most of the patients studied. Intravenous drug abuse was also associated with increased prostitution, incarceration, and previous suicide attempts. Psychiatric findings were influenced much less by the HIV diagnosis and much more by the presence or absence of a history of drug abuse.
在55例人类免疫缺陷病毒（HIV）血清反应阳性的孕妇样本中，药物滥用史与精神病理学增加显著相关，尤其是抑郁症和人格障碍。在大多数研究对象中，精神障碍先于HIV诊断出现。静脉注射药物滥用还与卖淫、监禁及既往自杀未遂增加有关。精神科检查结果受HIV诊断的影响小得多，而受药物滥用史的有无影响大得多。
