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苏联香烟烟草及主流烟雾中主要致癌物和生物碱的评估。

Assessment of major carcinogens and alkaloids in the tobacco and mainstream smoke of USSR cigarettes.

作者信息

Djordjevic M V, Sigountos C W, Hoffmann D, Brunnemann K D, Kagan M R, Bush L P, Safaev R D, Belitsky G A, Zaridze D

机构信息

Naylor Dana Institute for Disease Prevention, American Health Foundation, Valhalla, NY 10595.

出版信息

Int J Cancer. 1991 Feb 1;47(3):348-51. doi: 10.1002/ijc.2910470306.

Abstract

Tobacco and mainstream smoke of USSR cigarettes were analyzed for carcinogens. The pH values of suspensions of the tobacco (5.4-5.6) and the nitrate content of the tobaccos (0.4-1.7%) were as expected for flue-cured and sun-cured tobaccos and mixtures thereof. The nicotine levels of the cigarette tobaccos (0.76-0.94%) and total alkaloid content (0.85-1.08%) were relatively low compared with tobaccos used in Western European and US cigarettes. The concentrations of tobacco-specific N-nitrosamines in the cigarette tobaccos were also low (N'-nitrosonornicotine 0.36-0.85 microgram/g) compared with those in bright, oriental and blended cigarette tobaccos in Western countries (0.3-19 microgram/g). The 2 non-filter and 4 filter cigarettes from the USSR had slow burning rates and yielded 14.0-16.7 puffs/cigarette, while puff yields for commercial cigarettes in Western countries average less than or equal to 11 puffs/cigarette. Consequently, tar and benzo(a)pyrene yields in the smoke of all cigarettes as well as nitrosamine yields were high, especially in the smoke of the filter cigarettes. It appears that an increase in the burning rates of these cigarettes should lead to lower smoke yields.

摘要

对苏联香烟的烟草及主流烟雾中的致癌物进行了分析。烟草悬浮液的pH值(5.4 - 5.6)以及烟草中的硝酸盐含量(0.4 - 1.7%)符合烤烟、晒烟及其混合物的预期。与西欧和美国香烟所用烟草相比,卷烟烟草的尼古丁含量(0.76 - 0.94%)和总生物碱含量(0.85 - 1.08%)相对较低。与西方国家的烤烟、香料烟和混合型卷烟烟草(0.3 - 19微克/克)相比,卷烟烟草中烟草特有N - 亚硝胺的浓度也较低(N'-亚硝基降烟碱0.36 - 0.85微克/克)。苏联的2种非过滤嘴香烟和4种过滤嘴香烟燃烧速度较慢,每支香烟的吸口数为14.0 - 16.7口,而西方国家商业香烟的平均吸口数小于或等于11口/支。因此,所有香烟烟雾中的焦油、苯并(a)芘产量以及亚硝胺产量都很高,尤其是过滤嘴香烟的烟雾。看来提高这些香烟的燃烧速度会降低烟雾产量。

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