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鼻窦内腺癌内镜治疗的手术结果。

Surgical outcomes of endoscopic management of adenocarcinoma of the sinonasal cavity.

机构信息

Department of Otolaryngology Head and Neck Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, Australia.

出版信息

Rhinology. 2009 Dec;47(4):354-61. doi: 10.4193/Rhin08.222.

Abstract

OBJECTIVE

To report the surgical outcomes of endoscopic resection of adenocarcinomas of the Sinonasal cavity.

METHODS

Retrospective chart review of patients presenting with adenocarcinoma of the anterior skull base between 1998-2008. All patients who underwent wholly endoscopic resection were included in the study.

RESULTS

Twelve patients presented with adenocarcinoma involving the sino-nasal cavity. At diagnosis 6 patients were staged as a T2, 5 as a T3 and one as a T4. All of the patients had successful removal of the tumour entirely endoscopically. Three patients recurred: 2 locally and 1 with distant metastases. Overall, 11 patients are alive and free of disease and 1 patient dead of disease. We found an overall disease free survival rate and overall survival rate of 91.6%. The follow-up period ranged from 10 to 96 months with a median of 30 months.

CONCLUSION

Endoscopic management of adenocarcinoma of the sino-nasal cavity can be a viable treatment option to craniofacial resection. With the advancement in endoscopic equipment and surgeon skill, larger tumours may be managed wholly endoscopically.

摘要

目的

报告内镜切除鼻腔鼻窦腺癌的手术结果。

方法

对 1998 年至 2008 年间患有前颅底腺癌的患者进行回顾性图表审查。所有接受完全内镜切除的患者均纳入研究。

结果

12 例患者患有累及鼻-鼻窦的腺癌。诊断时,6 例患者分期为 T2,5 例患者分期为 T3,1 例患者分期为 T4。所有患者均成功地完全经内镜切除肿瘤。3 例患者复发:2 例局部复发,1 例远处转移。总的来说,11 例患者无病存活,1 例患者死于疾病。我们发现无病生存率和总生存率分别为 91.6%。随访时间为 10 至 96 个月,中位数为 30 个月。

结论

内镜治疗鼻腔鼻窦腺癌是颅面切除术的一种可行的治疗选择。随着内镜设备和外科医生技术的进步,更大的肿瘤可能可以完全经内镜治疗。

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