Department of Otolaryngology Head and Neck Surgery, The Queen Elizabeth Hospital, University of Adelaide, Adelaide, Australia.
Rhinology. 2009 Dec;47(4):354-61. doi: 10.4193/Rhin08.222.
To report the surgical outcomes of endoscopic resection of adenocarcinomas of the Sinonasal cavity.
Retrospective chart review of patients presenting with adenocarcinoma of the anterior skull base between 1998-2008. All patients who underwent wholly endoscopic resection were included in the study.
Twelve patients presented with adenocarcinoma involving the sino-nasal cavity. At diagnosis 6 patients were staged as a T2, 5 as a T3 and one as a T4. All of the patients had successful removal of the tumour entirely endoscopically. Three patients recurred: 2 locally and 1 with distant metastases. Overall, 11 patients are alive and free of disease and 1 patient dead of disease. We found an overall disease free survival rate and overall survival rate of 91.6%. The follow-up period ranged from 10 to 96 months with a median of 30 months.
Endoscopic management of adenocarcinoma of the sino-nasal cavity can be a viable treatment option to craniofacial resection. With the advancement in endoscopic equipment and surgeon skill, larger tumours may be managed wholly endoscopically.
报告内镜切除鼻腔鼻窦腺癌的手术结果。
对 1998 年至 2008 年间患有前颅底腺癌的患者进行回顾性图表审查。所有接受完全内镜切除的患者均纳入研究。
12 例患者患有累及鼻-鼻窦的腺癌。诊断时,6 例患者分期为 T2,5 例患者分期为 T3,1 例患者分期为 T4。所有患者均成功地完全经内镜切除肿瘤。3 例患者复发:2 例局部复发,1 例远处转移。总的来说,11 例患者无病存活,1 例患者死于疾病。我们发现无病生存率和总生存率分别为 91.6%。随访时间为 10 至 96 个月,中位数为 30 个月。
内镜治疗鼻腔鼻窦腺癌是颅面切除术的一种可行的治疗选择。随着内镜设备和外科医生技术的进步,更大的肿瘤可能可以完全经内镜治疗。