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鼻腔鼻窦内翻性乳头状瘤治疗方法的演变

An evolution in the management of sinonasal inverting papilloma.

作者信息

Han J K, Smith T L, Loehrl T, Toohill R J, Smith M M

机构信息

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226, U.S.A.

出版信息

Laryngoscope. 2001 Aug;111(8):1395-400. doi: 10.1097/00005537-200108000-00015.

DOI:10.1097/00005537-200108000-00015
PMID:11568575
Abstract

OBJECTIVE

We reviewed the 15-year experience of our institution (Medical College of Wisconsin, Milwaukee, WI) in managing sinonasal inverting papilloma, examining trends in diagnosis and treatment.

STUDY DESIGN

Retrospective.

METHODS

Thirty-seven patients with inverting papilloma were treated from 1986 to 1999. Demographic data, clinical presentations, pathological findings, surgical approaches and procedures, and recurrence rates were collected retrospectively. Each lesion was categorized into one of four groups based on computed tomography scans and endoscopic findings. This categorization was developed to compare various surgical approaches for tumors in each group.

RESULTS

Thirty-one patients had complete information for inclusion in our study. Nineteen patients were treated endoscopically with an average follow-up of 50 months. Eight patients were in group I, five were in group II, six were in group III, and no patients were in group IV. The recurrence rate for the endoscopic group was 10%. Twelve patients underwent lateral rhinotomy or sublabial degloving approach with an average follow-up of 58 months. Five patients were in group I, three patients were in group II, 1 patient was in group III, and three patients were in group IV. The recurrence rate for the external group was 8%. Difference in recurrence rates (P =.85) was not observed between the endoscopic and external approach groups. Regardless of approach, patients who had primary resection had a recurrence of 0%, whereas those with secondary resection had a recurrence of 17% (P =.10).

CONCLUSIONS

Technological advancements have led to a trend of detecting sinonasal inverting papilloma before extension beyond the sinonasal region. Difference in recurrence rates was not observed between the endoscopic and the external approach groups. Recurrence rates are lower for primary resection versus secondary resection, regardless of surgical approach.

摘要

目的

我们回顾了我院(威斯康星医学院,密尔沃基,威斯康星州)15年来诊治鼻窦内翻性乳头状瘤的经验,研究诊断和治疗的趋势。

研究设计

回顾性研究。

方法

1986年至1999年期间,37例内翻性乳头状瘤患者接受了治疗。回顾性收集人口统计学数据、临床表现、病理结果、手术方式及复发率。根据计算机断层扫描和内镜检查结果,将每个病变分为四组之一。这种分类旨在比较每组肿瘤的不同手术方式。

结果

31例患者有完整资料纳入本研究。19例患者接受了内镜治疗,平均随访50个月。8例患者属于I组,5例属于II组,6例属于III组,无患者属于IV组。内镜治疗组的复发率为10%。12例患者接受了鼻侧切开术或唇下翻瓣术,平均随访58个月。5例患者属于I组,3例属于II组,1例属于III组,3例属于IV组。外治法组的复发率为8%。内镜治疗组和外治法组之间未观察到复发率差异(P = 0.85)。无论采用何种方法,初次切除的患者复发率为0%,而二次切除的患者复发率为17%(P = 0.10)。

结论

技术进步导致鼻窦内翻性乳头状瘤在超出鼻窦区域扩散之前被检测到的趋势。内镜治疗组和外治法组之间未观察到复发率差异。无论采用何种手术方式,初次切除的复发率低于二次切除。

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