Taneja Rajesh
Pushpawati Singhania Research Institute, Press Enclave Road, Sheikh Sarai, Phase II, New Delhi 17, India.
Int Urogynecol J. 2010 Mar;21(3):321-4. doi: 10.1007/s00192-009-1045-0.
To differentiate between the pain originating from urinary bladder and that due to other pelvic organs, using intravesical instillations of 2% lignocaine solution.
Twenty-two women with pelvic pain received intravesical instillation of 20 ml of 2% lignocaine solution. The intensity of pain was recorded by using visual analogue scale (VAS) just before, at 2, 10 and 20 min after intravesical instillation. Women who experienced a drop in the VAS score by 50% were termed as responders. All these women underwent cystoscopy under anaesthesia.
Fifteen out of 22 (68.18%) women experienced a substantial reduction in the pain. Thirteen out of these 15 women had features suggestive of BPS/IC on cystoscopy. Out of the seven non-responders, two women were found to have endometriosis, four were diagnosed as pelvic inflammatory disease and one had diverticulitis.
Intravesical lignocaine appears to be useful in excluding patients with pelvic pain originating from organs other than the urinary bladder.
通过膀胱内灌注2%利多卡因溶液，区分源于膀胱的疼痛与其他盆腔器官引起的疼痛。
22名患有盆腔疼痛的女性接受了20毫升2%利多卡因溶液的膀胱内灌注。在膀胱内灌注前、灌注后2分钟、10分钟和20分钟，使用视觉模拟评分法（VAS）记录疼痛强度。VAS评分下降50%的女性被称为反应者。所有这些女性均在麻醉下接受膀胱镜检查。
22名女性中有15名（68.18%）疼痛明显减轻。这15名女性中有13名在膀胱镜检查时有提示膀胱疼痛综合征/间质性膀胱炎（BPS/IC）的特征。在7名无反应者中，2名女性被发现患有子宫内膜异位症，4名被诊断为盆腔炎，1名患有憩室炎。
膀胱内利多卡因似乎有助于排除源于膀胱以外器官的盆腔疼痛患者。
