Laboratoire des Matériaux Inorganiques (LMI, UMR UBP-CNRS 6002), Université Blaise Pascal (Clermont-Ferrand), 24, Avenue des Landais, 63177, Aubière cedex, France.
Anal Bioanal Chem. 2010 Jan;396(1):315-25. doi: 10.1007/s00216-009-3274-y. Epub 2009 Nov 21.
Two-dimensional layered inorganic solids, such as cationic clays and layered double hydroxides (LDHs), also defined as anionic clays, have open structures which are favourable for interactions with enzymes and which intercalate redox mediators. This review aims to show the interest in clays and LDHs as suitable host matrices likely to immobilize enzymes onto electrode surfaces for biosensing applications. It is meant to provide an overview of the various types of electrochemical biosensors that have been developed with these 2D layered materials, along with significant advances over the last several years. The different biosensor configurations and their specific transduction procedures are discussed.
二维层状无机固体，如阳离子粘土和层状双氢氧化物（LDHs），也被定义为阴离子粘土，具有有利于与酶相互作用的开放结构，并可以嵌入氧化还原介体。本综述旨在展示粘土和 LDH 作为合适的宿主基质的兴趣，这些基质有可能将酶固定在电极表面上用于生物传感应用。它旨在提供使用这些 2D 层状材料开发的各种类型的电化学生物传感器的概述，以及过去几年的重要进展。讨论了不同的生物传感器配置及其特定的转换程序。
