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多发性硬化症患者双侧额内侧额叶病变致排尿障碍。

Micturitional disturbance due to bilateral medial frontal lobe lesions in a patient with multiple sclerosis.

机构信息

Department of Neurology, School of Medicine, Fukushima Medical University, Fukushima, Japan.

出版信息

Neurol Sci. 2010 Apr;31(2):205-7. doi: 10.1007/s10072-009-0189-5.

DOI:10.1007/s10072-009-0189-5
PMID:19936880
Abstract

A 41-year-old man with multiple sclerosis (MS) complained of nocturnal enuresis at the third exacerbation. Neurological examination revealed echopraxia, forced grasp reflexes and palmo-mental reflexes. The urodynamic studies showed neither spinal cord nor peripheral nerve involvements. His brain magnetic resonance images (MRIs) revealed new lesions at the bilateral medial frontal lobes. The intravenous methylprednisolone therapy improved nocturnal enuresis and made brain MRI lesions smaller and gone. In addition to frequently observed spinal cord lesions, we should consider some medial frontal lesions to be responsible for micturitional disturbance in patients with MS.

摘要

一位 41 岁的多发性硬化症(MS)患者在第三次恶化时抱怨夜间遗尿。神经系统检查显示回声模仿、强制抓握反射和手掌心理反射。尿动力学研究显示无脊髓或周围神经受累。他的脑部磁共振成像(MRI)显示双侧额内侧叶有新的病变。静脉注射甲基强的松龙治疗改善了夜间遗尿,并使脑部 MRI 病变变小和消失。除了经常观察到的脊髓病变外,我们还应考虑一些额内侧病变是导致 MS 患者排尿障碍的原因。

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本文引用的文献

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Urodynamic findings in primary progressive multiple sclerosis are associated with increased volumes of plaques and atrophy in the central nervous system.原发性进行性多发性硬化症的尿动力学检查结果与中枢神经系统斑块体积增加和萎缩有关。
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LESIONS ON THE ANTERIOR FRONTAL LOBES AND DISTURBANCES OF MICTURITION AND DEFAECATION.额叶前部病变与排尿和排便障碍
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Relationship of bladder dysfunction to lesion site in multiple sclerosis.
多发性硬化症中膀胱功能障碍与病变部位的关系。
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Micturitional disturbance after acute hemispheric stroke: analysis of the lesion site by CT and MRI.急性半球性卒中后的排尿障碍:通过CT和MRI对病变部位的分析
J Neurol Sci. 1996 Apr;137(1):47-56. doi: 10.1016/0022-510x(95)00322-s.
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Desmopressin in the management of nocturia in patients with multiple sclerosis. A double-blind, crossover trial.去氨加压素治疗多发性硬化症患者夜尿症的疗效观察:一项双盲交叉试验
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