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噬菌体疗法根除慢性细菌性前列腺炎中的粪肠球菌——病例报告。

Eradication of Enterococcus faecalis by phage therapy in chronic bacterial prostatitis--case report.

机构信息

Urological and Andrological Clinic UROGEN, 42-600, Tarnowskie Góry, Poland.

出版信息

Folia Microbiol (Praha). 2009 Sep;54(5):457-61. doi: 10.1007/s12223-009-0064-z. Epub 2009 Nov 24.

DOI:10.1007/s12223-009-0064-z
PMID:19937220
Abstract

The treatment of three patients suffering from chronic bacterial prostatitis who were qualified for an experimental phage therapy protocol managed at the Phage Therapy Unit in Wrocław is described. They had previously been treated unsuccessfully with long-term targeted antibiotics, autovaccines, and laser biostimulation. Rectal application of phage lysates targeted against Enterococcus faecalis cultured from the prostatic fluid gave encouraging results regarding bacterial eradication, abatement of clinical symptoms of prostatitis, and lack of early disease recurrence.

摘要

本文描述了在弗罗茨瓦夫噬菌体治疗科接受实验性噬菌体治疗方案治疗的 3 例慢性细菌性前列腺炎患者的治疗情况。这些患者先前接受过长期靶向抗生素、自体疫苗和激光生物刺激治疗,但均未成功。经直肠给予针对从前列腺液中培养的粪肠球菌的噬菌体裂解物的治疗,在消除细菌、减轻前列腺炎临床症状以及无早期疾病复发方面取得了令人鼓舞的结果。

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