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小儿创伤性脑损伤床边脑血流动力学监测的实践要点

Practical aspects of bedside cerebral hemodynamics monitoring in pediatric TBI.

作者信息

Figaji Anthony A

机构信息

Division of Neurosurgery, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.

出版信息

Childs Nerv Syst. 2010 Apr;26(4):431-9. doi: 10.1007/s00381-009-1036-y.

Abstract

INTRODUCTION

Disturbances in cerebral hemodynamics may have a profound influence on secondary injury after traumatic brain injury (TBI), and many therapies in the neurocritical care unit may adversely affect cerebral blood flow. However, the clinician is often unaware of this when it occurs because practical methods for monitoring cerebral hemodynamics by the bedside have been lacking. Current imaging studies only provide a snapshot of the brain at one point in time, giving limited information about a dynamic condition.

DISCUSSION

This review will focus on key pathophysiological concepts required to understand changes in cerebral hemodynamics after TBI and the principles, potential benefits, and limitations of currently available bedside monitoring techniques, including transcranial Doppler, autoregulation, and local/regional cerebral blood flow.

摘要

引言

脑血流动力学紊乱可能对创伤性脑损伤(TBI)后的继发性损伤产生深远影响,神经重症监护病房中的许多治疗方法可能会对脑血流量产生不利影响。然而,当这种情况发生时,临床医生往往并未意识到,因为一直缺乏床边监测脑血流动力学的实用方法。目前的影像学研究仅能提供某一时刻大脑的快照,关于动态情况的信息有限。

讨论

本综述将聚焦于理解TBI后脑血流动力学变化所需的关键病理生理概念,以及当前可用的床边监测技术的原理、潜在益处和局限性,包括经颅多普勒、自动调节以及局部/区域脑血流量。

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