MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou, China.
Plant Signal Behav. 2009 Sep;4(9):902-4. doi: 10.4161/psb.4.9.9531.
Programmed cell death (PCD) is a genetically-controlled disassembly of the cell. In animal systems, the central core execution switch for apoptotic PCD is the activation of caspases (Cysteine-containing Aspartate-specific proteases). Accumulating evidence in recent years suggests the existence of caspase-like activity in plants and its functional involvement in various types of plant PCD, although no functional homologs of animal caspases were identified in plant genome. In this mini-review, we will cover the recent results on the existence of plant caspase-like proteases and introduce major technologies used in detecting the activation of caspase-like proteases during plant PCD.
程序性细胞死亡(PCD)是一种受基因控制的细胞解体过程。在动物系统中,凋亡性 PCD 的中央核心执行开关是半胱天冬氨酸特异性蛋白酶(caspases)的激活。近年来越来越多的证据表明,植物中存在类似半胱天冬氨酸蛋白酶的活性,并且其在各种类型的植物 PCD 中具有功能相关性,尽管在植物基因组中未鉴定出动物 caspase 的功能同源物。在这篇迷你综述中,我们将介绍植物中存在的类似半胱天冬氨酸蛋白酶的最新研究结果,并介绍在植物 PCD 过程中检测类似半胱天冬氨酸蛋白酶活性的主要技术。