Guliaeva S S, Voloshchuk I N, Mokrysheva N G, Rozhinskaia L Ia
Arkh Patol. 2009 Sep-Oct;71(5):53-5.
The paper describes a case of maldiagnosis of giant-cell tumor in a patient with parathyroid osteodystrophy, in this connection elbow joint resection and replacement were made. Parathyroid adenoma with the symptoms of primary hyperparathyroidism was diagnosed only two years after surgery. Progression of diseases was accompanied by severe bone changes and the development of urolithiasis complicated by chronic renal failure. Thus, the interpretation of bone tissue changes without considering clinical and laboratory data led to the unwarranted surgical intervention and the late diagnosis of primary hyperparathyroidism. Differential diagnosis of a giant-cell tumor should be made, by obligatorily considering clinical and laboratory data, including the parameters of calcium metabolism.
本文描述了一名甲状旁腺骨营养不良患者被误诊为巨细胞瘤的病例，为此进行了肘关节切除和置换手术。术后两年才诊断出患有原发性甲状旁腺功能亢进症状的甲状旁腺腺瘤。疾病进展伴有严重的骨骼变化以及并发慢性肾衰竭的尿路结石形成。因此，在不考虑临床和实验室数据的情况下对骨组织变化进行解读，导致了不必要的手术干预以及原发性甲状旁腺功能亢进的延迟诊断。巨细胞瘤的鉴别诊断应通过强制考虑临床和实验室数据，包括钙代谢参数来进行。
