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蒙古两起羊痘病毒病疫情描述。

A description of two outbreaks of capripoxvirus disease in Mongolia.

机构信息

Roslin Institute/Royal (Dick) School of Veterinary Studies, Easter Bush Veterinary Centre, Roslin, Midlothian, Edinburgh, UK.

出版信息

Vet Microbiol. 2010 May 19;142(3-4):427-31. doi: 10.1016/j.vetmic.2009.10.018. Epub 2009 Oct 28.

DOI:10.1016/j.vetmic.2009.10.018
PMID:19939588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2866252/
Abstract

Mongolia had no reported cases of capripoxvirus disease from 1977 until an outbreak of sheeppox in 2006-2007 and then goatpox in 2008. The two outbreaks occurred in geographically distant areas of Mongolia and, most strikingly, were highly species-specific. The 2006-2007 sheeppox outbreak affected no goats and the 2008 goatpox outbreak affected no sheep despite communal herding. The diseases were diagnosed using the polymerase chain reaction and virus neutralisation test. The P32 gene of the Mongolian sheeppox and goatpox viruses from the recent outbreaks were sequenced and compared with an archived 1967 strain of Goatpox virus from Mongolia. The P32 gene of the 2006-2007 Mongolian Sheeppox virus strain was identical to previously published sheeppox strains. The P32 gene of the 2008 Mongolian Goatpox virus strain was identical to the gene from virus isolated from recent goatpox outbreaks in China and Vietnam. The archived Mongolian Goatpox virus strain was unique.

摘要

1977 年以来,蒙古未曾报告过羊痘病毒病病例,直到 2006-2007 年暴发绵羊痘,随后在 2008 年暴发山羊痘。这两起疫情发生在蒙古地理位置相隔甚远的地区,且最显著的是,它们具有高度的物种特异性。2006-2007 年的绵羊痘疫情未波及山羊,2008 年的山羊痘疫情也未波及绵羊,尽管存在混群放牧。这两种疾病均使用聚合酶链反应和病毒中和试验进行诊断。对蒙古最近暴发的绵羊痘和山羊痘病毒的 P32 基因进行测序,并与蒙古存档的 1967 年山羊痘病毒株进行比较。2006-2007 年蒙古绵羊痘病毒株的 P32 基因与先前公布的绵羊痘病毒株完全相同。2008 年蒙古山羊痘病毒株的 P32 基因与从中国和越南最近山羊痘暴发中分离出的病毒的基因完全相同。蒙古存档的山羊痘病毒株则是独一无二的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/5fa7701d9a73/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/a724e5ae33f7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/e45e7305cac1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/5fa7701d9a73/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/a724e5ae33f7/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/e45e7305cac1/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1588/2866252/5fa7701d9a73/gr3.jpg

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