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精液中IgG和IgA水平的测定:对不育症生物学研究的意义

[IgG and IgA levels determination in semen liquid: interest for the biological investigation of infertility].

作者信息

Limam M, Zorgati Mm, Zarrouk A, Ali S Ben Hadj, Bouras S, Ammar S Ben

机构信息

Laboratoire central de biologie médicale, Institut Pasteur, Tunis, Tunisie.

出版信息

Ann Biol Clin (Paris). 2009 Nov-Dec;67(6):613-7. doi: 10.1684/abc.2009.0379.

Abstract

We studied the relationship between spermogram parameters and biochemical elements in seminal plasma. In this way we searched an association between immunoglobulin levels in seminal plasma and spermogram parameters. The spermogram is usually performed in our laboratory for investigation of infertility. Using immunonephelometry, we measured immunoglobulin (Ig) G and A levels in the seminal plasma of 17 patients. Averages levels of IgG and IgA were 83.3 and 33.6 mg/L, respectively. IgG and IgA levels appeared to be significantly different (p = 0.001), and were significantly associated. A correlation between IgG values and coiled tails percentage was noted in patients having IgA below 20 mg/L (p < 0,001). In conclusion, the measurement of IgG and IgA levels in seminal plasma might constitute a valuable diagnosis tool for the evaluation of infertility.

摘要

我们研究了精液参数与精浆中生化元素之间的关系。通过这种方式,我们探寻了精浆中免疫球蛋白水平与精液参数之间的关联。在我们实验室,精液分析通常用于不孕症的检查。我们采用免疫比浊法,测定了17例患者精浆中的免疫球蛋白(Ig)G和A水平。IgG和IgA的平均水平分别为83.3mg/L和33.6mg/L。IgG和IgA水平存在显著差异(p = 0.001),且具有显著相关性。在IgA低于20mg/L的患者中,观察到IgG值与卷曲尾百分比之间存在相关性(p < 0.001)。总之,测定精浆中IgG和IgA水平可能成为评估不孕症的一项有价值的诊断工具。

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