表观遗传学：环境因素与2型糖尿病之间的分子联系。 - Suppr

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超能文献

Epigenetics: a molecular link between environmental factors and type 2 diabetes.

作者信息

Ling Charlotte, Groop Leif

机构信息

Department of Clinical Sciences, Lund University Diabetes Center, Lund University, Malmö, Sweden.

出版信息

Diabetes. 2009 Dec;58(12):2718-25. doi: 10.2337/db09-1003.

DOI:10.2337/db09-1003

PMID:19940235

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2780862/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/643c/2780862/d1b4abab21d6/zdb0120959580001.jpg

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High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats.高脂饮食诱导的肥胖改变了大鼠瘦素启动子的甲基化模式。

J Physiol Biochem. 2009 Mar;65(1):1-9. doi: 10.1007/BF03165964.

ATP-citrate lyase links cellular metabolism to histone acetylation.ATP-柠檬酸裂解酶将细胞代谢与组蛋白乙酰化联系起来。

Science. 2009 May 22;324(5930):1076-80. doi: 10.1126/science.1164097.

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Genes Dev. 2009 Apr 15;23(8):975-85. doi: 10.1101/gad.1742509.

Bmi-1 regulates the Ink4a/Arf locus to control pancreatic beta-cell proliferation.Bmi-1通过调控Ink4a/Arf基因座来控制胰腺β细胞增殖。

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