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圆锥髓内神经鞘瘤并与神经组织紧密粘连。

Intramedullary schwannoma of the conus medullaris complicated by dense adhesion to neural tissue.

作者信息

Ohtonari Tatsuya, Nishihara Nobuharu, Ota Taisei, Ota Shinzo, Koyama Tsunemaro

机构信息

Department of Spinal Surgery, Brain Attack Center Ota Memorial Hospital, Okinogami-cho, Fukuyama, Hiroshima, Japan.

出版信息

Neurol Med Chir (Tokyo). 2009 Nov;49(11):536-8. doi: 10.2176/nmc.49.536.

Abstract

A 29-year-old man presented with an intramedullary schwannoma of the conus medullaris manifesting as an 8-month history of mild bladder dysfunction, sexual impotence, and paresthesia in the buttocks. Subtotal removal of the lesion was achieved, as part of the tumor showed dense adhesion to the rostral neural tissue, with only postoperative transient deterioration of bladder dysfunction. Intramedullary schwannoma, especially involving the conus medullaris and the proximal spinal cord, is relatively rare and the pathogenesis and pathophysiology are unclear. Complete resection is often advised to avoid recurrence, but tumor adhesion to neural tissue sometimes renders complete resection difficult, and may create the risk of unacceptable operative morbidity. The present case shows that transient neurological deterioration may occur even with just subtotal removal, leaving the adherent part. Therefore, recognition of the particular features and the strategy for treatment in intramedullary schwannoma of the conus medullaris is essential for making appropriate decisions on the degree of removal.

摘要

一名29岁男性患者,患有圆锥髓内神经鞘瘤,表现为8个月的轻度膀胱功能障碍、性功能障碍和臀部感觉异常病史。由于肿瘤部分与头侧神经组织紧密粘连,仅实现了病变的次全切除,术后仅出现膀胱功能障碍的短暂恶化。髓内神经鞘瘤,尤其是累及圆锥和脊髓近端的神经鞘瘤相对罕见,其发病机制和病理生理学尚不清楚。通常建议进行完整切除以避免复发,但肿瘤与神经组织的粘连有时会使完整切除变得困难,并可能产生不可接受的手术并发症风险。本病例表明,即使仅行次全切除并保留粘连部分,也可能发生短暂的神经功能恶化。因此,认识圆锥髓内神经鞘瘤的特殊特征和治疗策略对于就切除程度做出适当决策至关重要。

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