Department of Biomedical Engineering, Catholic University of America, Washington, DC 20064, USA.
Neurodegener Dis. 2009;6(5-6):240-51. doi: 10.1159/000262444. Epub 2009 Nov 26.
Several clinical studies on chronic stroke conducted with end-effector-based robots showed improvement of the motor function in the affected arm. Compared to end-effector-based robots, exoskeleton robots provide improved guidance of the human limb and are better suited to train task-oriented movements with a large range of motions.
To test whether intensive arm training with the arm exoskeleton ARMin I is feasible with chronic-stroke patients and whether it improves motor function in the paretic arm.
Three single cases with chronic hemiparesis resulting from unilateral stroke (at least 14 months after stroke). A-B design with 2 weeks of multiple baseline measurements (A), 8 weeks of training (B) with repetitive measurements and a follow-up measurement 8 weeks after training. The training included shoulder and elbow movements with the robotic rehabilitation device ARMin I. Two subjects had three 1-hour sessions per week and 1 subject received five 1-hour sessions per week. The main outcome measurement was the upper-limb part of the Fugl-Meyer Assessment (FMA).
The ARMin training was well tolerated by the patients, and the FMA showed moderate, but significant improvements for all 3 subjects (p < 0.05). Most improvements were maintained 8 weeks after discharge.
This study indicates that intensive training with an arm exoskeleton is feasible with chronic-stroke patients. Moderate improvements were found in all 3 subjects, thus further clinical investigations are justified.
几项基于末端效应器的机器人对慢性中风患者进行的临床研究表明,患侧手臂的运动功能得到了改善。与末端效应器机器人相比,外骨骼机器人为人体肢体提供了更好的引导,更适合训练具有大范围运动的面向任务的运动。
测试使用手臂外骨骼 ARMin I 对慢性中风患者进行集中手臂训练是否可行,以及是否能改善患侧手臂的运动功能。
纳入 3 例由单侧中风引起的慢性偏瘫患者(中风后至少 14 个月)。采用 A-B 设计,包括 2 周的多次基线测量(A)、8 周的训练(B)和重复测量,以及训练结束后 8 周的随访测量。训练包括使用机器人康复设备 ARMin I 进行肩部和肘部运动。2 名患者每周接受 3 次 1 小时的治疗,1 名患者每周接受 5 次 1 小时的治疗。主要的结果测量是 Fugl-Meyer 上肢评估(FMA)。
患者对 ARMin 训练的耐受性良好,所有 3 名患者的 FMA 均显示出中等但显著的改善(p<0.05)。大多数改善在出院后 8 周内得到维持。
本研究表明,慢性中风患者可以进行集中的手臂外骨骼训练。所有 3 名患者均有中度改善,因此需要进一步的临床研究。