Department of Public Health, Medical School, University of Patras, Patras, Greece.
Epidemiol Infect. 2010 Jul;138(7):1025-31. doi: 10.1017/S0950268809991257. Epub 2009 Nov 27.
An outbreak of hepatitis A virus (HAV) infection affected Roma populations living in three prefectures of northeastern Greece. Between July and November 2007, 124 cases were reported. We carried out investigations to characterize the pathogen, to identify the source of infection and the route of transmission. Using the RT-PCR technique, HAV strains of the same genotype were detected in all sera from a subset of patients with acute disease. These showed more than 99.8% identity, suggesting a common source. A questionnaire was also completed to collect clinical and epidemiological information. The outbreak affected mainly Roma children aged <10 years. An inspection of Roma settlements showed that poor sanitary conditions were associated with the HAV outbreak.
甲型肝炎病毒 (HAV) 感染爆发影响了居住在希腊东北部三个州的罗姆人。2007 年 7 月至 11 月期间,报告了 124 例病例。我们进行了调查,以确定病原体、感染源和传播途径。使用 RT-PCR 技术,在一组急性疾病患者的血清中检测到了相同基因型的 HAV 株。这些菌株的相似度超过 99.8%,表明存在共同来源。还完成了一份问卷,以收集临床和流行病学信息。疫情主要影响了年龄<10 岁的罗姆儿童。对罗姆人定居点的检查表明,卫生条件差与 HAV 爆发有关。