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产妇要求下的剖宫产:健康初产妇及其婴儿的风险与益处

Caesarean section on maternal request: risks and benefits in healthy nulliparous women and their infants.

作者信息

Dahlgren Leanne S, von Dadelszen Peter, Christilaw Jan, Janssen Patricia A, Lisonkova Sarka, Marquette Gerald P, Liston Robert M

机构信息

Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver BC.

Department of Specialized Women's Health, University of British Columbia, Vancouver BC.

出版信息

J Obstet Gynaecol Can. 2009 Sep;31(9):808-817. doi: 10.1016/S1701-2163(16)34299-2.

Abstract

OBJECTIVE

To determine the risks and benefits of an elective Caesarean section (CS) at term in healthy nulliparous women.

METHODS

We conducted a population-based cohort study of deliveries between 1994 and 2002. Using bivariate and multivariable techniques, we compared maternal and neonatal outcomes in healthy nulliparous women who had undergone elective pre-labour CS (using breech presentation as a surrogate) with those in women who had undergone spontaneous labour with anticipated vaginal delivery (SL) at full term.

RESULTS

There were 1046 deliveries in the pre-labour CS group and 38 021 in the SL group. Life-threatening maternal morbidity was similar in each group. Life-threatening neonatal morbidity was decreased in the CS group (RR 0.34; 99% CI 0.12 to 0.97). Subgroup analysis of the SL group by mode of delivery demonstrated the increased neonatal risk was associated with operative vaginal delivery and intrapartum CS but not spontaneous vaginal delivery.

CONCLUSION

An elective pre-labour Caesarean section in a nulliparous woman at full term decreased the risk of life-threatening neonatal morbidity compared with spontaneous labour with anticipated vaginal delivery. However, the 63% of women with spontaneous labour who achieved a spontaneous vaginal delivery would not have benefited from delivery by Caesarean section. Further research is needed to better identify women with an increased likelihood of an operative vaginal or intrapartum Caesarean section, as this may assist maternity caregivers in decision-making about childbirth. Further research is also needed to determine if these findings can be confirmed in a prospective study.

摘要

目的

确定健康未生育女性足月选择性剖宫产的风险和益处。

方法

我们对1994年至2002年间的分娩情况进行了一项基于人群的队列研究。运用双变量和多变量技术,我们比较了接受选择性分娩前剖宫产(以臀位作为替代)的健康未生育女性与足月自然分娩且预期经阴道分娩的女性的母婴结局。

结果

分娩前剖宫产组有1046例分娩,自然分娩组有38021例。两组中危及生命的孕产妇发病率相似。剖宫产组危及生命的新生儿发病率降低(相对危险度0.34;99%可信区间0.12至0.97)。对自然分娩组按分娩方式进行亚组分析表明,新生儿风险增加与阴道助产和分娩期剖宫产有关,而与自然阴道分娩无关。

结论

与预期经阴道分娩的自然分娩相比,未生育女性足月选择性分娩前剖宫产降低了危及生命的新生儿发病率。然而,63%自然分娩且实现自然阴道分娩的女性不会从剖宫产中受益。需要进一步研究以更好地识别阴道助产或分娩期剖宫产可能性增加的女性,因为这可能有助于产科护理人员进行分娩决策。还需要进一步研究以确定这些发现能否在前瞻性研究中得到证实。

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