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老年综合评估与多维方法。胃肠道疾病老年患者的新视角。

The Comprehensive Geriatric Assessment and the multidimensional approach. A new look at the older patient with gastroenterological disorders.

机构信息

Geriatric Unit & Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, Viale Cappuccini 1, San Giovanni Rotondo, Italy.

出版信息

Best Pract Res Clin Gastroenterol. 2009;23(6):829-37. doi: 10.1016/j.bpg.2009.10.001.

Abstract

The Comprehensive Geriatric Assessment (CGA) is a multidimensional, usually interdisciplinary, diagnostic process intended to determine an elderly person's medical, psychosocial, and functional capacity and problems with the objective of developing an overall plan for treatment and short- and long-term follow-up. The potential usefulness of the CGA in evaluating treatment and follow-up of older patients with gastroenterological disorders is unknown. In the paper we reported the efficacy of a Multidimensional-Prognostic Index (MPI), calculated from information collected by a standardized CGA, in predicting mortality risk in older patients hospitalized with upper gastrointestinal bleeding and liver cirrhosis. Patients underwent a CGA that included six standardized scales, i.e. Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL), Short-Portable Mental Status Questionnaire (SPMSQ), Mini-Nutritional Assessment (MNA), Exton-Smith Score (ESS) and Comorbity Index Rating Scale (CIRS), as well as information on medication history and cohabitation, for a total of 63 items. The MPI was calculated from the integrated total scores and expressed as MPI 1=low risk, MPI 2=moderate risk and MPI 3=severe risk of mortality. Higher MPI values were significantly associated with higher short- and long-term mortality in older patients with both upper gastrointestinal bleeding and liver cirrhosis. A close agreement was found between the estimated mortality by MPI and the observed mortality. Moreover, MPI seems to have a greater discriminatory power than organ-specific prognostic indices such as Rockall and Blatchford scores (in upper gastrointestinal bleeding patients) and Child-Plugh score (in liver cirrhosis patients). All these findings support the concept that a multidimensional approach may be appropriate for the evaluation of older patients with gastroenterological disorders, like it has been reported for patients with other pathological conditions.

摘要

综合老年评估(CGA)是一种多维的、通常是跨学科的诊断过程,旨在确定老年人的医疗、心理社会和功能能力以及问题,目的是制定治疗和短期及长期随访的总体计划。CGA 在评估老年胃肠疾病患者的治疗和随访中的潜在有用性尚不清楚。在本文中,我们报告了一种多维预后指数(MPI)的疗效,该指数是根据标准化 CGA 收集的信息计算得出的,可预测因上消化道出血和肝硬化住院的老年患者的死亡风险。患者接受了 CGA 检查,包括 6 个标准化量表,即日常生活活动(ADL)、工具性日常生活活动(IADL)、短期便携精神状态问卷(SPMSQ)、微型营养评估(MNA)、埃克斯顿-史密斯评分(ESS)和合并症指数评分量表(CIRS),以及药物史和同居信息,共 63 项。MPI 是根据综合总分计算得出的,分为 MPI1=低风险、MPI2=中度风险和 MPI3=高死亡风险。在患有上消化道出血和肝硬化的老年患者中,较高的 MPI 值与短期和长期死亡率显著相关。MPI 估计的死亡率与观察到的死亡率密切相关。此外,MPI 似乎比器官特异性预后指数(如上消化道出血患者的 Rockall 和 Blatchford 评分和肝硬化患者的 Child-Plugh 评分)具有更大的区分能力。所有这些发现都支持这样一种概念,即多维方法可能适合评估患有胃肠疾病的老年患者,就像已经报道的其他病理情况的患者一样。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e773/4986608/2c895351587d/nihms-809194-f0001.jpg

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