Edward L. Ginzton Lab., Stanford Univ., Stanford, CA, USA.
IEEE Trans Ultrason Ferroelectr Freq Control. 2009 Oct;56(10):2145-56. doi: 10.1109/TUFFC.2009.1297.
State-of-the-art 3-D medical ultrasound imaging requires transmitting and receiving ultrasound using a 2-D array of ultrasound transducers with hundreds or thousands of elements. A tight combination of the transducer array with integrated circuitry eliminates bulky cables connecting the elements of the transducer array to a separate system of electronics. Furthermore, preamplifiers located close to the array can lead to improved receive sensitivity. A combined IC and transducer array can lead to a portable, high-performance, and inexpensive 3-D ultrasound imaging system. This paper presents an IC flip-chip bonded to a 16 x 16-element capacitive micromachined ultrasonic transducer (CMUT) array for 3-D ultrasound imaging. The IC includes a transmit beamformer that generates 25-V unipolar pulses with programmable focusing delays to 224 of the 256 transducer elements. One-shot circuits allow adjustment of the pulse widths for different ultrasound transducer center frequencies. For receiving reflected ultrasound signals, the IC uses the 32-elements along the array diagonals. The IC provides each receiving element with a low-noise 25-MHz-bandwidth transimpedance amplifier. Using a field-programmable gate array (FPGA) clocked at 100 MHz to operate the IC, the IC generated properly timed transmit pulses with 5-ns accuracy. With the IC flip-chip bonded to a CMUT array, we show that the IC can produce steered and focused ultrasound beams. We present 2-D and 3-D images of a wire phantom and 2-D orthogonal cross-sectional images (Bscans) of a latex heart phantom.
最先进的 3D 医学超声成像是通过使用具有数百或数千个元件的二维超声换能器阵列来发射和接收超声。换能器阵列与集成电路的紧密结合消除了将换能器阵列的元件连接到单独的电子系统的庞大电缆。此外,靠近阵列的前置放大器可以提高接收灵敏度。集成的 IC 和换能器阵列可以实现便携式、高性能和低成本的 3D 超声成像系统。本文提出了一种与 16x16 元电容式微机械超声换能器 (CMUT) 阵列倒装芯片的 IC 用于 3D 超声成像。该 IC 包括一个发射波束形成器,可生成具有可编程聚焦延迟的 25V 单极脉冲,最多可对 256 个换能器元件中的 224 个进行聚焦。单触发电路允许针对不同的超声换能器中心频率调整脉冲宽度。对于接收反射的超声信号,该 IC 使用沿阵列对角线的 32 个元件。该 IC 为每个接收元件提供一个低噪声的 25MHz 带宽跨阻放大器。使用以 100MHz 时钟运行的现场可编程门阵列 (FPGA) 来操作 IC,该 IC 可以以 5ns 的精度生成定时正确的发射脉冲。通过将 IC 倒装芯片与 CMUT 阵列结合,我们展示了该 IC 可以产生定向和聚焦的超声束。我们展示了一个金属丝体模的 2D 和 3D 图像,以及一个乳胶心脏体模的 2D 正交横截面图像(B 扫描)。