Hoff W S, D'Amelio L F, Tinkoff G H, Lucke J F, Rhodes M, Diamond D L, Indeck M, Smith J S
Division of Trauma, Lehigh Valley Hospital Center, Allentown, Pennsylvania 18103.
Surg Gynecol Obstet. 1991 Mar;172(3):175-80.
Trauma complicates 6 to 7 per cent of all pregnancies, but fetal demise secondary to maternal trauma occurs much less frequently. This study was done to analyze the incidence of fetal demise as a function of 21 maternal characteristics determined within the first 24 hours after trauma. Nine instances of fetal demise were identified from 73 pregnant patients with trauma admitted to four Level I trauma centers from a combined data base of 30,000 patients. Maternal factors examined by logistic regression were Injury Severity Score (ISS), Trauma Score (TS), Abbreviated Injury Scale (AIS), fluid requirements in the initial 24 hours, systolic blood pressure (SBP), heart rate (HR), hemoglobin, hematocrit and arterial blood gas analysis. Fetal demise was found to be associated with increasing ISS, increasing face and abdominal AIS, increasing fluid requirements, maternal acidosis and maternal hypoxia. Standard maternal laboratory and physiologic parameters, such as hemoglobin and hematocrit, oxygen and hemoglobin saturation, partial pressure of carbon dioxide, SBP and HR were not predictive. The TS was also found to be nonpredictive.
创伤在所有妊娠中占比6%至7%,但因母体创伤导致的胎儿死亡则较为罕见。本研究旨在分析创伤后24小时内确定的21项母体特征与胎儿死亡发生率之间的关系。从四个一级创伤中心收治的73例创伤孕妇中,在30000例患者的综合数据库中确定了9例胎儿死亡病例。通过逻辑回归分析的母体因素包括损伤严重度评分(ISS)、创伤评分(TS)、简明损伤定级标准(AIS)、最初24小时的液体需求量、收缩压(SBP)、心率(HR)、血红蛋白、血细胞比容和动脉血气分析。研究发现,胎儿死亡与ISS升高、面部和腹部AIS升高、液体需求量增加、母体酸中毒和母体缺氧有关。标准的母体实验室和生理参数,如血红蛋白和血细胞比容、血氧和血红蛋白饱和度、二氧化碳分压、SBP和HR,并无预测价值。TS也无预测价值。