The Key Laboratory of Forest Genetics and Gene Engineering, College of Forest Resources and Environment, Nanjing Forestry University, Nanjing, JS 210037, China.
Trends Genet. 2010 Jan;26(1):39-46. doi: 10.1016/j.tig.2009.11.004. Epub 2009 Nov 26.
One of the fundamental tasks in biology is the identification of genes that control the structure and developmental pattern of complex traits and their responses to the environment during trait development. Functional mapping provides a statistical means for detecting quantitative trait loci (QTLs) that underlie developmental traits, such as growth trajectories, and for testing the interplay between gene action and development. Here we describe how functional mapping and studies of plant ontology can be integrated so as to elucidate the expression mechanisms of QTLs that control plant growth, morphology, development, and adaptation to changing environments. This approach can also be used to construct an evo-devo framework for inferring the evolution of developmental traits.
生物学的基本任务之一是鉴定那些控制复杂性状结构和发育模式及其在性状发育过程中对环境响应的基因。功能作图为检测发育性状（如生长轨迹）的数量性状位点（QTL）提供了一种统计方法，并可用于检验基因作用与发育之间的相互作用。在这里，我们描述了如何整合功能作图和植物本体论研究，以阐明控制植物生长、形态、发育和适应环境变化的 QTL 的表达机制。这种方法还可用于构建一个进化发育框架，以推断发育性状的进化。
