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脂滴终于得到了一点尊重。

Lipid droplets finally get a little R-E-S-P-E-C-T.

作者信息

Farese Robert V, Walther Tobias C

机构信息

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.

出版信息

Cell. 2009 Nov 25;139(5):855-60. doi: 10.1016/j.cell.2009.11.005.

DOI:10.1016/j.cell.2009.11.005
PMID:19945371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3097139/
Abstract

Long underappreciated as important cellular organelles, lipid droplets are finally being recognized as dynamic structures with a complex and interesting biology. In light of this newfound respect, we discuss emerging views on lipid droplet biology and speculate on the major advances to come.

摘要

长期以来未被充分重视的脂质滴,作为重要的细胞器,终于被视作具有复杂而有趣生物学特性的动态结构。鉴于这一新近获得的认可,我们将讨论有关脂质滴生物学的新观点,并推测未来的重大进展。

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Biofuels. ExxonMobil fuels Venter's efforts to run vehicles on algae-based oil.生物燃料。埃克森美孚公司为文特尔利用藻类油驱动车辆的努力提供燃料支持。
Science. 2009 Jul 24;325(5939):379. doi: 10.1126/science.325_379a.
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Coatomer-dependent protein delivery to lipid droplets.依赖包被蛋白的蛋白质向脂滴的递送。
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J Neuroinflammation. 2025 Jul 19;22(1):190. doi: 10.1186/s12974-025-03517-0.
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PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis.磷脂酰肌醇-4-磷酸(PI(4)P)招募CIDE蛋白,以促进脂肪生成和肝脂肪变性过程中单室脂滴的形成。
Proc Natl Acad Sci U S A. 2025 Jul 8;122(27):e2504219122. doi: 10.1073/pnas.2504219122. Epub 2025 Jul 3.
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