凯马特超市的顾客请注意：7号过道有商品大减价！
Attention K-Mart shoppers: blowout on Aisle 7!
作者信息
Griffith Leslie C
机构信息
Department of Biology and National Center for Behavioral Genomics, Brandeis University, Waltham, MA 02454-9110, USA.
出版信息
Neuron. 2009 Nov 25;64(4):443-5. doi: 10.1016/j.neuron.2009.11.009.
Abstract
The mechanistic basis of arousal is controversial. In this issue of Neuron, Lebestky et al.'s new study in Drosophila, where dopamine has been shown to be involved in several types of attentional processes, demonstrates that it independently regulates distinct types of arousal. These data provide evidence for molecularly convergent, but anatomically divergent, task-specific arousal circuits.
摘要
觉醒的机制基础存在争议。在本期《神经元》杂志中，莱贝茨基等人在果蝇身上开展的新研究表明，多巴胺参与了多种类型的注意力过程，该研究还证明多巴胺能独立调节不同类型的觉醒。这些数据为分子层面趋同但解剖学层面不同的任务特异性觉醒回路提供了证据。
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本文引用的文献
1
Two different forms of arousal in Drosophila are oppositely regulated by the dopamine D1 receptor ortholog DopR via distinct neural circuits.果蝇中两种不同形式的觉醒由多巴胺 D1 受体同源物 DopR 通过不同的神经回路进行相反的调节。
Neuron. 2009 Nov 25;64(4):522-36. doi: 10.1016/j.neuron.2009.09.031.
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Light-arousal and circadian photoreception circuits intersect at the large PDF cells of the Drosophila brain.光唤醒和昼夜节律光感受回路在果蝇大脑的大型PDF细胞处相交。
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