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顺势疗法基础研究中的实验报告(REHBaR)——作者详细指南

Reporting experiments in homeopathic basic research (REHBaR)--a detailed guideline for authors.

作者信息

Stock-Schröer B, Albrecht H, Betti L, Endler P C, Linde K, Lüdtke R, Musial F, van Wijk R, Witt C, Baumgartner S

机构信息

Karl and Veronica Carstens-Foundation, D-Essen, Germany.

Department of Agro-Environmental Science and Technology, Faculty of Agriculture, Bologna University, I-Bologna, Italy.

出版信息

Homeopathy. 2009 Oct;98(4):287-298. doi: 10.1016/j.homp.2009.09.006.

Abstract

BACKGROUND

Reporting experiments in basic research in homeopathy is an important issue as comprehensive description of what exactly was done is required. So far, there is no guideline for authors available, unlike criteria catalogues common in clinical research.

METHODS

A Delphi Process was conducted, including a total of five rounds, three rounds of adjusting and phrasing plus two consensus conferences. European researchers who published experimental work within the last five years were involved.

RESULTS

A checklist of 23 items was obtained and supplemented with detailed examples emphasizing what each item implies. Background, objectives and possible hypotheses should be given in the part 'introduction'. Special emphasis is put on the 'materials and methods' section, where a detailed description of chosen controls, object of investigation, experimental setup, replication, parameters, intervention, allocation, blinding, and statistical methods is required. The section 'results' should present sufficient details on analysed data, descriptive as well as inferential. Authors should discuss their results and give an interpretation in the context of current evidence.

CONCLUSION

A guideline for Reporting Experiments in Homeopathic Basic Research (REHBaR) was compiled to be applied by authors when preparing their manuscripts, and to be used by scientific journals in the reviewing process. Furthermore the guideline is a commitment to a certain minimum quality level needed in basic research, e.g. blinding and randomisation. Feedback is encouraged on applicability, strength and limitations of the list to enable future revisions.

摘要

背景

顺势疗法基础研究中的实验报告是一个重要问题,因为需要对具体所做的事情进行全面描述。到目前为止,与临床研究中常见的标准目录不同,尚无可供作者使用的指南。

方法

进行了德尔菲法,共包括五轮,三轮调整和措辞以及两轮共识会议。涉及在过去五年内发表过实验性研究的欧洲研究人员。

结果

获得了一份包含23项内容的清单,并辅以详细示例以强调每项内容的含义。 “引言”部分应给出背景、目标和可能的假设。特别强调“材料与方法”部分,其中需要对所选对照、研究对象、实验设置、重复、参数、干预、分配、盲法和统计方法进行详细描述。 “结果”部分应提供关于分析数据的足够详细信息,包括描述性和推断性信息。作者应讨论其结果并结合当前证据进行解释。

结论

编制了顺势疗法基础研究实验报告指南(REHBaR),供作者在撰写稿件时应用,并供科学期刊在审稿过程中使用。此外,该指南致力于基础研究所需的一定最低质量水平,例如盲法和随机化。鼓励对该清单的适用性、优势和局限性提供反馈,以便未来进行修订。

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