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致心律失常性右室心肌病中无法标测的室性心动过速:采用高分辨率电解剖标测技术阐明关键的孤立延迟成分。

An unmappable ventricular tachycardia in the arrhythmogenic right ventricular cardiomyopathy: elucidation of critical isolated delayed components with high-resolution electroanatomical mapping.

机构信息

Cardiovascular Center, Kyoto-Katsura Hospital, Nishikyo-ku, Kyoto 615-8256, Japan.

出版信息

Europace. 2010 Feb;12(2):279-81. doi: 10.1093/europace/eup374. Epub 2009 Nov 27.

DOI:10.1093/europace/eup374
PMID:19946111
Abstract

Unmappable ventricular tachycardia (VT) is a challenge in the management of arrhythmogenic right ventricular cardiomyopathy (ARVC). We report a feasible strategy for a curative ablation. In the present case with ARVC, the clinical VT showed a single morphology of left bundle branch block with inferior axis. Neither activation mapping nor entrainment mapping could be done because of instability of the haemodynamics. Furthermore, pace mapping could not be obtained due to electrically unexcitable scars covering with the RV. We found isolated delayed components (IDCs) in the diastolic phase recorded within the scar areas. Electroanatomical mapping (CARTO) with tiered decreasing voltage definition revealed that IDCs were delineated on the narrow conducting channels along or between the complete scars (amplitude < or =0.1 mV). Isolated delayed components on the narrow channels were targeted under the guidance with CARTO. After 11 radiofrequency applications, the clinical VT was eliminated. Moreover, epsilon waves recorded on the 12-lead electrocardiogram disappeared. No ventricular tachyarrhythmia was recognized at 6-month follow-up. Isolated delayed component ablation with high-resolution CARTO map was feasible and provided a curative approach in the treatment of an unmappable VT in ARVC.

摘要

无法标测的室性心动过速(VT)是心律失常性右室心肌病(ARVC)管理中的一个挑战。我们报告了一种可行的根治性消融策略。在本例 ARVC 中,临床 VT 表现为左束支传导阻滞伴下壁轴的单一形态。由于血流动力学不稳定,无法进行激动标测或拖带标测。此外,由于 RV 覆盖的电无兴奋性瘢痕,无法获得起搏标测。我们发现,在瘢痕区域内记录的舒张期有孤立的延迟成分(IDC)。分层递减电压定义的电解剖标测(CARTO)显示,在完整瘢痕的狭窄传导通道上或之间(幅度 < 或 =0.1 mV)可描绘 IDC。在 CARTO 的指导下,对狭窄通道上的孤立延迟成分进行了靶向消融。11 次射频消融后,临床 VT 消失。此外,12 导联心电图上的 ε 波消失。6 个月随访时未发现室性心动过速。使用高分辨率 CARTO 图进行孤立的延迟成分消融是可行的,为 ARVC 中无法标测的 VT 提供了一种根治方法。

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