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脑脂肪栓塞与“星芒状”模式:一例报告

Cerebral fat embolism and the "starfield" pattern: a case report.

作者信息

Aravapalli Amit, Fox James, Lazaridis Christos

机构信息

Department of Internal Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA.

出版信息

Cases J. 2009 Nov 19;2:212. doi: 10.1186/1757-1626-2-212.

Abstract

Nearly all long-bone fractures are accompanied by some form of fat embolism. The rare complication of clinically significant fat embolism syndrome, however, occurs in only 0.9-2.2% of cases. The clinical triad of fat embolism syndrome consists of respiratory distress, altered mental status, and petechial rash. Cerebral fat embolism causes the neurologic involvement seen in fat embolism syndrome. A 19-year-old African-American male was admitted with gunshot wounds to his right hand and right knee. He had diffuse hyperactive deep tendon reflexes, bilateral ankle clonus and decerebrate posturing with a Glasgow Coma Scale (GCS) score of 4T. Subsequent MRI of the brain showed innumerable punctate areas of restricted diffusion consistent with "starfield" pattern. On a 10-week follow up he has a normal neurological examination and he is discharged home. Despite the severity of the neurologic insult upon initial presentation, the majority of case reports on cerebral fat embolism illustrate that cerebral dysfunction associated with cerebral fat embolism is reversible. When neurologic deterioration occurs in the non-head trauma patient, then a systemic cause such as fat emboli should be considered. We describe a patient with non-head trauma who demonstrated the classic "starfield" pattern on diffusion-weighted MRI imaging.

摘要

几乎所有长骨骨折都伴有某种形式的脂肪栓塞。然而,临床上具有显著意义的脂肪栓塞综合征这种罕见并发症仅发生在0.9 - 2.2%的病例中。脂肪栓塞综合征的临床三联征包括呼吸窘迫、意识状态改变和瘀点皮疹。脑脂肪栓塞导致了脂肪栓塞综合征中所见的神经功能受累。一名19岁非裔美国男性因右手和右膝枪伤入院。他有弥漫性亢进的深腱反射、双侧踝阵挛以及去大脑强直姿势,格拉斯哥昏迷量表(GCS)评分为4T。随后的脑部MRI显示无数点状扩散受限区域,符合“星野”模式。在10周的随访中,他的神经系统检查正常,随后出院回家。尽管初始表现时神经损伤严重,但大多数关于脑脂肪栓塞的病例报告表明,与脑脂肪栓塞相关的脑功能障碍是可逆的。当非头部创伤患者出现神经功能恶化时,应考虑诸如脂肪栓子等全身性原因。我们描述了一名非头部创伤患者,其在扩散加权MRI成像上表现出典型的“星野”模式。

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