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枪伤所致长骨骨折后发生的脑脂肪栓塞综合征

Cerebral fat embolism syndrome after long bone fracture due to gunshot injury.

作者信息

Duran Latif, Kayhan Servet, Kati Celal, Akdemir Hizir Ufuk, Balci Kemal, Yavuz Yucel

机构信息

Department of Emergency Medicine, University of Ondokuz Mayıs, School of Medicine, Samsun, Turkey.

Department of Pulmonology, University of Ondokuz Mayıs, School of Medicine, Samsun, Turkey.

出版信息

Indian J Crit Care Med. 2014 Mar;18(3):167-9. doi: 10.4103/0972-5229.128707.

DOI:10.4103/0972-5229.128707
PMID:24701067
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3963200/
Abstract

Cerebral fat embolism syndrome is a lethal complication of long-bone fractures and clinically manifasted with respiratory distress, altered mental status, and petechial rash. We presented a 20-year-old male admitted with gun-shot wounds to his left leg. Twenty-four hours after the event, he had generalized tonic clonic seizures, decorticate posture and a Glascow Coma Scale of seven with localization of painful stimuli. Subsequent magnetic resonance imaging of the brain showed a star-field pattern defining multiple lesions of restricted diffusion. On a 4-week follow-up, he had returned to normal neurological function. Despite the severity of the neurological condition upon initial presentation, the case cerebral fat embolism illustrates that, cerebral dysfunction associated with cerebral fat embolism illustrates reversible.

摘要

脑脂肪栓塞综合征是长骨骨折的一种致命并发症,临床症状表现为呼吸窘迫、精神状态改变和瘀点皮疹。我们报告了一名20岁男性,因左腿枪伤入院。受伤24小时后,他出现全身性强直阵挛性癫痫发作、去皮质姿势,格拉斯哥昏迷量表评分为7分,疼痛刺激有定位反应。随后的脑部磁共振成像显示出星芒状图案,提示多个扩散受限的病灶。在4周的随访中,他的神经功能已恢复正常。尽管最初就诊时神经状况严重,但该例脑脂肪栓塞表明,与脑脂肪栓塞相关的脑功能障碍是可逆的。

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本文引用的文献

1
Post-traumatic fulminant paradoxical fat embolism syndrome in conjunction with asymptomatic atrial septal defect: a case report and review of the literature.创伤后暴发性矛盾性脂肪栓塞综合征合并无症状房间隔缺损:一例报告及文献复习
J Med Case Rep. 2011 Apr 10;5:142. doi: 10.1186/1752-1947-5-142.
2
Cerebral fat embolism after bilateral total knee replacement arthroplasty -A case report-.双侧全膝关节置换术后脑脂肪栓塞——病例报告。
Korean J Anesthesiol. 2010 Dec;59 Suppl(Suppl):S207-10. doi: 10.4097/kjae.2010.59.S.S207. Epub 2010 Dec 31.
3
Fat embolism syndrome in long bone fracture--clinical experience in a tertiary referral center in Taiwan.
微出血在脑脂肪栓塞中呈现出特征性分布。
Insights Imaging. 2021 Mar 31;12(1):42. doi: 10.1186/s13244-021-00988-6.
4
Histopathological evaluation of autopsy cases with isolated pulmonary fat embolism (IPFE): is cardiopulmonary resuscitation a main cause of death in IPFE?孤立性肺脂肪栓塞(IPFE)尸检病例的组织病理学评估:心肺复苏是IPFE死亡的主要原因吗?
Open Access Emerg Med. 2019 Jun 7;11:121-127. doi: 10.2147/OAEM.S194340. eCollection 2019.
长骨骨折脂肪栓塞综合征-台湾一家三级转诊中心的临床经验。
J Chin Med Assoc. 2010 Aug;73(8):407-10. doi: 10.1016/S1726-4901(10)70088-5.
4
Cerebral fat embolism and the "starfield" pattern: a case report.脑脂肪栓塞与“星芒状”模式:一例报告
Cases J. 2009 Nov 19;2:212. doi: 10.1186/1757-1626-2-212.
5
Therapeutic aspects of fat embolism syndrome.脂肪栓塞综合征的治疗方面
Injury. 2006 Oct;37 Suppl 4:S68-73. doi: 10.1016/j.injury.2006.08.042.
6
Early diagnosis of cerebral fat embolism syndrome by diffusion-weighted MRI (starfield pattern).通过扩散加权磁共振成像(星芒状模式)早期诊断脑脂肪栓塞综合征
Stroke. 2001 Dec 1;32(12):2942-4.
7
Fat embolism syndrome in isolated femoral fractures: does timing of nailing influence incidence?单纯股骨干骨折中的脂肪栓塞综合征:髓内钉固定时机是否影响发病率?
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8
Prolonged coma due to cerebral fat embolism: report of two cases.脑脂肪栓塞所致的长期昏迷:两例报告
J Accid Emerg Med. 2000 Mar;17(2):144-6. doi: 10.1136/emj.17.2.144.