The role of childhood parent figure loss in the etiology of adult depression: findings from a prospective longitudinal study.

The underlying question of this study is whether childhood parental loss between infancy and sixth grade is a predictor of adult depression at age 26 years when a rating of loss severity is used. The loss rating considered the length of the separation/loss, the familiarity of substitute caregivers, the primary or supporting role of the lost parent figure, and traumatic features of the loss. The study also investigated the role of gender, developmental timing of the loss, life stress, SES, prior parental care and attachment history, and follow-up family relationships in the pathways between loss and depression. Results are reported from a prospective longitudinal study of children (N = 164) born into poverty. Measures were collected prenatally through age 26 years and included multiple methods and multiple reporters. Results indicated that the most robust predictor of adult depression was loss history between 5 years old and grade 2. Earlier and later measures of loss were not related to adult depression. However, intervening loss experiences predicted change in depression scores from childhood to adulthood. Loss continued to predict adult depression after controlling for SES, maternal life stress, participant life stress, gender, early caregiving, and follow up family functioning. This study found no significant gender differences. These results suggest that loss is a risk factor for adult depression for both boys and girls and that the quality of early and later caregiving do not entirely buffer children from the effects of parental loss.