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[不同年龄心肌梗死后硬化大鼠脂质过氧化的特征]

[Features of lipid peroxidation in rats of different age with postinfarction cardiosclerosis].

作者信息

Rebrova T Iu, Afanas'ev S A, Medvedeva O D

出版信息

Adv Gerontol. 2009;22(2):292-5.

PMID:19947393
Abstract

Results of research of a state of lipid peroxidation (LP) system at rats by age of 4 and 12 months with postinfarction cardiosclerosis are presented in this work. It has been shown, that in the remote terms after an experimental myocardium infarct, age-dependent alteration of the LP and antioxidizing enzymes activity were observed. Also distinction in expressiveness of the LP processes in the intact animals in these age groups was revealed. Such age features probably cause various intensities of the LP and the state of antioxidant protection at postinfarction remodeling of heart.

摘要

本文展示了对4个月龄和12个月龄患有心肌梗死后心脏硬化的大鼠脂质过氧化(LP)系统状态的研究结果。结果表明,在实验性心肌梗死后的远期,观察到LP和抗氧化酶活性存在年龄依赖性变化。此外,还揭示了这些年龄组中完整动物LP过程表达的差异。这种年龄特征可能导致心脏梗死后重塑时LP的不同强度以及抗氧化保护状态。

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