Tang Zhiynan, Zhao Weihong, Wang Lin, Ma Qing
Institute of Physiology and Pharmacology, Medical School of Ningbo University, Ningbo 315211, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Oct;26(5):959-62.
In this experimental study, the AC impedance of isolated gastrocnemius was measured with an impendance analyzer of Agilent 4294A, and the effect of simulated weightlessness on the dielectric properties of the cells in isolated rat sural muscle was investigated by analyzing the dielectric numerical characters with the use of dielectric spectroscopy, the Cole-Cole plots, the spectrum of loss factor and loss tangent, as well as the spectrum of conductivity imaginary part. The results demonstrated that 10 weeks' simulated weightlessness caused some changes; for example, both permittivity at low frequency (epsilonL) and permittivity increment (deltaepsilon) were reduced, and conductivity at high frequency (kappa(h)) was also reduced; at the same time, conductivity increment (deltakappa) was reduced, too. The first characteristic frequency (f(C1)) decreased, while the second characteristic frequency(f(C2)) increased. All of the peak of loss factor, the peak of loss tangent, and the maximum of conductivity imaginary part were reduced. These data indicated that the reduction of dielectric properties of skeletal muscles was induced by weightlessness.
在本实验研究中,使用安捷伦4294A阻抗分析仪测量离体腓肠肌的交流阻抗,并通过介电谱、科尔-科尔图、损耗因子和损耗角正切谱以及电导率虚部谱分析介电数值特征,研究模拟失重对离体大鼠腓肠肌细胞介电特性的影响。结果表明,10周的模拟失重引起了一些变化;例如,低频介电常数(εL)和介电常数增量(δε)均降低,高频电导率(κ(h))也降低;同时,电导率增量(Δκ)也降低。第一特征频率(f(C1))降低,而第二特征频率(f(C2))升高。损耗因子峰值、损耗角正切峰值和电导率虚部最大值均降低。这些数据表明失重诱导了骨骼肌介电特性的降低。