Zhao Hui, Fang Bo, Chen Jingjing, Liu Wei, Liu Lirong, Wang Ruirui
Research Center of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2009 Oct;26(5):1039-42.
An amphiphilic LDL adsorbent was synthesized with dietary fiber as the carrier, laurylamine as hydrophobic group and 3-Chloro-2-hydroxylpropysodium sulfonate as sulphonation reagent. The effects of reaction time, reaction temperature and amount of 3-Chloro-2-hydroxylpropysodium sulfonate on SO4(2-) content were studied, and the required preparations were made. The condition for adsorption was obtained by investigating the influence of adsorbent amount and adsorption time. The results show that the adsorption percentages for the removal of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) are 49.6%, 60.0% and 18.2%, respectively. This amphiphilic adsorbent possesses a better selectivity in removing cholesterol.
以膳食纤维为载体、月桂胺为疏水基团、3-氯-2-羟基丙磺酸钠为磺化试剂合成了一种两亲性低密度脂蛋白吸附剂。研究了反应时间、反应温度和3-氯-2-羟基丙磺酸钠用量对SO4(2-)含量的影响，并进行了所需的制备。通过考察吸附剂用量和吸附时间的影响，得出了吸附条件。结果表明，去除总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）和高密度脂蛋白胆固醇（HDL-C）的吸附率分别为49.6%、60.0%和18.2%。这种两亲性吸附剂在去除胆固醇方面具有较好的选择性。
