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[月桂酸修饰的低密度脂蛋白吸附剂的研究]

[Study on LDL adsorbent modified by lauric acid].

作者信息

Cong Haixia, Du Longbing, Fang Bo, You Chao

机构信息

Chemical Engineering Research Center, ECUST, Shanghai 200237, China.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2010 Jun;27(3):671-4.

PMID:20649041
Abstract

A hydrophobic low-density lipoprotein cholesterol (LDL-C) adsorbent was synthesized with lauric acid and chitosan. The condition for adsorption was obtained by investigating the influence of adsorbent amount and adsorption time. The results of adsorption in vitro showed that the average adsorption rates for total cholesterol (TC), LDL-C, high-density lipoprotein cholesterol (HDL-C) and total protein (TP) were 47.7%, 84.7%, 18.1% and 5.9% respectively. The adsorbent possesses good selectivity in removing LDL-C.

摘要

用月桂酸和壳聚糖合成了一种疏水性低密度脂蛋白胆固醇(LDL-C)吸附剂。通过考察吸附剂用量和吸附时间的影响,得出了吸附条件。体外吸附结果表明,对总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)和总蛋白(TP)的平均吸附率分别为47.7%、84.7%、18.1%和5.9%。该吸附剂在去除LDL-C方面具有良好的选择性。

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